Melissa officinalis (M. officinalis) Herbs Melissa officinalis (M. officinalis) REISHI MUSHROOM Use: Nourish & support adrenal function. Promotes healthy immunity, increases resistance to colds, and reduces inflammation. DRUG INTERACTION: Avoid with hypertensive medications and blood thinners. HISTORY: Known as the herb of “spiritual power”. Used in China for more than 2000 years. DOSAGE: Capsule or Tablet: 3-9 grams of the dried mushroom Tincture: 2-4 mL of reishi in water 2-3 times daily USE: Restlessness, Insomnia, reduce anxiety, promote a sense of calm, alleviate digestive upset, reduction of cold sores DRUG INTERACTION: Do not use with sedatives HISTORY: Part of the mint family, perennial herb, used medicinally for centuries DOSAGE: Capsule: 400 mg once daily Tea: 60 drops of tincture to 8 ounce cup of tea Cream: 1% of a 70:1 freeze-dried water-soluable extract Essential Oil: Apply 1-2 drops to affected area RESEARCH Chuang MH, Chiou SH, Huang CH, Yang WB, Wong CH. The lifespan-promoting effect of acetic acid and Reishi polysaccharide. Bioorg Med Chem. 2009 Nov 15;17(22):7831-40. Thyagarajan-Sahu A, Lane B, Sliva D. ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK. BMC Complement Altern Med. 2011;11:74. RESEARCH Scholey A, Gibbs A, Neale C, et al. Anti-Stress Effects of Lemon Balm-Containing Foods. Nutrients. 2014;6(11):4805-4821. doi:10.3390/nu6114805. Akbarzadeh M, Dehghani M, Moshfeghy Z, Emamghoreishi M, Tavakoli P, Zare N. Effect of Melissa officinalis Capsule on the Intensity of Premenstrual Syndrome Symptoms in High School Girl Students. Nursing and Midwifery Studies. 2015;4(2):e27001. doi:10.17795/nmsjournal27001. Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Mediterranean Journal of Nutrition and Metabolism. 2011;4(3):211-218. doi:10.1007/s12349-010-0045-4.