Lab 2 أعزائي الطلبة هذه الورقة تحتوي فقط على ما قيل عن هذه الصور زيادة عن النظري وأي معلومة ذكرت في النظري وتكررت في العملي لن تجدوها مذكورة هنا ولكنكم مطالبون بمعرفتها بالتأكيد

Fibrinoid necrosis Chronic inflammatory cells attacking the vessel wall Robbins

TB-caseating necrosis Cheese-like Robbins Emphysematous changes

Fibrillary background due to glial cell processes WebPath Macrophages in liquefactive necrosis of brain (brain infarction) Neurons (large nucleus, prominent nucleolus and bulky cytoplasm) Small nuclei are glial cells

Brain atrophy Narrowed gyri Widened sulci WebPath Changes are mainly frontally (Alzheimer case)

Kidney coagulative necrosis Robbins glomerulus

Alzheimer WebPath Tau proteins are the components of these “neurofibrillary tangles”

Degeneration and absence of nuclei MI WebPath Inflammatory cells Degeneration and absence of nuclei

Cardiac hypertrophy WebPath

Barret esophagus WebPath Columnar cell metaplasia ..may be like stomach foveolar epithelium or goblet cells like intestine (intestinal metaplasia) glands

Calcification (arrows) Stroma (connective tissue) WebPath Glands of stomach body/fundus (zymogenic granules in chief cells) vessel

Lipid-laden macrophages in bone marrow (storage disease) WebPath

Tingible body macrophages eating apoptotic fragments of lymphocytes in thymus WebPath

Robbins

Fatty liver (steatosis) Non-alcoholic steatohepatitis (NASH) Alcoholic steatohepatitis (ASH) WebPath

Mallory hyaline inclusions (keratin protein) (characteristic but not only in alcoholic liver disease) WebPath

Perl’s or Prussian blue stain ..Iron…blue Hemosiderosis is due to hereditary hemochromatosis or other causes such as multiple blood transfusions (as in thalassemia major cases) WebPath

Lipofuscin in liver…atrophy or autophagy…etc. WebPath Needs Perl’s stain to exclude iron Liver (trabeculae of polygonal hepatocytes)

Hepatocyte atrophy with lipofuscin WebPath