Figure 3. Changes from baseline in activated CD4<sup>+</sup> T cells (% CD4<sup>+</sup>CD25<sup>+</sup>) during the 52-week intervention period in the intention-to-treat population from a BITE pilot study (*P = .036, change from baseline). The Immunomodulatory Nutritional Intervention NR100157 Reduced CD4+ T-Cell Decline and Immune Activation: A 1-Year Multicenter Randomized Controlled Double-Blind Trial in HIV-Infected Persons Not Receiving Antiretroviral Therapy (The BITE Study) Clin Infect Dis. 2013;57(1):139-146. doi:10.1093/cid/cit171 Clin Infect Dis | © The Author 2013. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com. 1