Figure 2. Systematic review: chronological presentation of allergic reaction rates in recipients (n) of equine botulinum antitoxin (BAT) products by study,

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Figure 2. Systematic review: chronological presentation of allergic reaction rates in recipients (n) of equine botulinum antitoxin (BAT) products by study, 1980–2016. Allergic reactions included all reports of allergic reaction including anaphylaxis. For the clinical trial data, any reaction fitting the criteria of allergic or anaphylactic reaction was counted as such, even if not reported as allergic or anaphylactic in the trial report. From: Workgroup Report by the Joint Task Force Involving American Academy of Allergy, Asthma & Immunology (AAAAI); Food Allergy, Anaphylaxis, Dermatology and Drug Allergy (FADDA) (Adverse Reactions to Foods Committee and Adverse Reactions to Drugs, Biologicals, and Latex Committee); and the Centers for Disease Control and Prevention Botulism Clinical Treatment Guidelines Workgroup—Allergic Reactions to Botulinum Antitoxin: A Systematic Review Clin Infect Dis. 2017;66(suppl_1):S65-S72. doi:10.1093/cid/cix827 Clin Infect Dis | Published by Oxford University Press for the Infectious Diseases Society of America 2017. This work is written by (a) US Government employee(s) and is in the public domain in the US.This Open Access article contains public sector information licensed under the Open Government Licence v2.0 (http://www.nationalarchives.gov.uk/doc/open-government-licence/version/2/). 1