Triple-Negative Breast Cancer

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Triple-Negative Breast Cancer Jonathan D. Marotti, Francine B. de Abreu, Wendy A. Wells, Gregory J. Tsongalis The American Journal of Pathology Volume 187, Issue 10, Pages 2133-2138 (October 2017) DOI: 10.1016/j.ajpath.2017.05.018 Copyright © 2017 American Society for Investigative Pathology Terms and Conditions

Figure 1 Morphologic variants of triple-negative breast cancer (TNBC) with different genetic alterations. A: TNBC with basal-like histologic features containing a prominent stromal lymphocytic infiltrate; this tumor had MYC amplification. B: TNBC with apocrine differentiation and a PI3KCA mutation. The tumor cells have abundant eosinophilic cytoplasm, round nuclei, and prominent nucleoli. Scale bars: 100 μm. Original magnification with hematoxylin and eosin: ×520 (A); ×560 (B). The American Journal of Pathology 2017 187, 2133-2138DOI: (10.1016/j.ajpath.2017.05.018) Copyright © 2017 American Society for Investigative Pathology Terms and Conditions