From: Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery:A Retrospective Cohort Study with Interrupted.

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From: Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery:A Retrospective Cohort Study with Interrupted Time–Series Analysis Anesthes. 2015;122(3):560-570. doi:10.1097/ALN.0000000000000556 Figure Legend: Transfusion algorithm. Point-of-care (POC) tests consist of ROTEM® (Rotation Thromboelastometry; Tem International GmBH, Munich, Germany) and Plateletworks® (Helena Laboratories, Beaumont, TX) systems. A10-EXTEM (clot amplitude at 10 min in EXTEM assay; at <35 mm implies impaired clot formation due to low fibrinogen levels, low platelet count, or impaired platelet function), A10-FIBTEM (clot firmness amplitude at 10 min in FIBTEM assay; ≤7 mm confirms low fibrinogen levels), and CT-EXTEM (clotting time in EXTEM assay; ≥100 s implied poor clot initiation possibly due to reduced coagulation factor levels or reduced thrombin generation) are ROTEM® measures. Functioning platelet count is obtained by the Plateletworks® assay. During the last month of the study, fibrinogen concentrate was used in place of cryoprecipitate. ACT = activated clotting time; CPB = cardiopulmonary bypass; PCC = prothrombin complex concentrate; RBC = red blood cell; RV = right ventricle. Date of download: 3/8/2018 Copyright © 2018 American Society of Anesthesiologists. All rights reserved.