Small channels and large trials

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Presentation transcript:

Small channels and large trials JHJ Wokke, MD, J van Gijn, FRCPE  The Lancet  Volume 350, (December 1997) DOI: 10.1016/S0140-6736(97)90047-7 Copyright © 1997 Elsevier Ltd Terms and Conditions

Neuromuscular junction of a patient with the slow-channel syndrome. A prolonged opening time of the acetylcholine receptor ion channel causes increased calcium influx leading to destruction of postsynaptic juntional folds (*). To the left a nerve terminal is seen overlying normal folds. The Lancet 1997 350, DOI: (10.1016/S0140-6736(97)90047-7) Copyright © 1997 Elsevier Ltd Terms and Conditions

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