One-lung ventilation: For how long?

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Presentation transcript:

One-lung ventilation: For how long? Celal Tekinbas, MD, Hulya Ulusoy, MD, Esin Yulug, MD, PhD, Mehmet Muharrem Erol, MD, Ahmet Alver, PhD, Engin Yenilmez, PhD, Sukran Geze, MD, Murat Topbas, MD The Journal of Thoracic and Cardiovascular Surgery Volume 134, Issue 2, Pages 405-410 (August 2007) DOI: 10.1016/j.jtcvs.2007.05.003 Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Blood MDA assay. Data are expressed as mean ± standard deviation. *P < .010 versus other groups; **P < .05 control group versus occlusion group; ***P < .005 O1 versus O2. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 MDA levels in collapsing and contralateral lungs. Data are expressed as mean ± standard deviation. *P < .010 sham versus other groups; **P < .05 Cx versus Ox; ***P < .005 O1 versus O2 and O3. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 MPO activity in collapsing and contralateral lungs. *P < .010 sham versus other groups; **P < .005 O1 versus O2 and O3; ***P < .01 C2 versus O2. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Light microscopic photomicrograph showed interstitial edema (arrow), inflammatory cell infiltration(*), and alveolar structure damage in the collapsed lung in the O3. (Hematoxylin and eosin, original magnification ×100.) The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 Light microscopic photomicrograph showed lighter inflammatory cell infiltration and alveolar structure damage (arrow) in the contralateral lung in the O3. (Hematoxylin and eosin, original magnification ×200.) The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 6 Histologic findings in collapsed and contralateral lung. *P < .010 sham versus other groups; **P < .05 Cx versus Ox; ***P < .005 O1 versus O2 and O3. The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 7 Electron micrograph showed localized significant vacuolation, and loss in lamellar bodies (arrow) was observed in type 2 pneumocytes in collapsed lungs in the O3 (original magnification ×5000). The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 8 Decrease of vacuolation and lamellar bodies (arrow) were observed in type 2 pneumocytes in the contralateral lung in the O3 (original magnification ×10,000). The Journal of Thoracic and Cardiovascular Surgery 2007 134, 405-410DOI: (10.1016/j.jtcvs.2007.05.003) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions