IBS-D -- From Diagnosis to Management

Snapshot of IBS-D

The Diagnostic Challenges of IBS-D

Rome IV Diagnostic Criteria for IBS

Rome IV Diagnostic Testing Recommendations

Practical Approach to the Workup

Key Components of the Patient History

Diagnostic Approach

Emerging Biomarkers

IBS-D Treatment Options

Low-FODMAP Diet vs Australian Diet

A Low FODMAP Diet vs Modified NICE Guidelines in US Adults With IBS-D

Gluten-Free Diet

Probiotics Putative Mechanisms of Action

Pharmacologic Therapies

Loperamide in IBS-D

Antispasmodics

Global Relief of IBS Symptoms With TCAs or SSRIs

Bile Acid Sequestrants

Eluxadoline for IBS-D

Safety of Eluxadoline in Patients With IBS-D

Rifaximin

Repeat Treatment With Rifaximin TARGET 3

Alosetron for IBS-D

Case 5-Year History of Symptoms

Abbreviations

Abbreviations (cont)