How I treat the antiphospholipid syndrome

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How I treat the antiphospholipid syndrome by Bill Giannakopoulos, and Steven A. Krilis Blood Volume 114(10):2020-2030 September 3, 2009 ©2009 by American Society of Hematology

Treatment algorithm for the thrombotic and obstetric complications associated with persistently positive antiphospholipid antibodies. Treatment algorithm for the thrombotic and obstetric complications associated with persistently positive antiphospholipid antibodies. Readers are referred to current evidence-based consensus guidelines60 for the management of the various acute coronary syndromes, with and without coronary artery stenting, and myocardial infarction. Bill Giannakopoulos, and Steven A. Krilis Blood 2009;114:2020-2030 ©2009 by American Society of Hematology

A case of catastrophic APS with involvement of the ampulla of Vater. A case of catastrophic APS with involvement of the ampulla of Vater. (A) Morphologic appearance (on endoscopic examination) of ampulla of Vater, which is grossly edematous and unusual in appearance. (B) Ampullary biopsy showing small-vessel thrombosis. (Olympus BX41 microscope, objective lense used was the Olympus UPLANF 40×/0.75NA dry, original magnification ×400, H&E stain; camera: NIKON COOLPIX 995, image acquistion software: Olympus CAMEDIA Master.) (C) Resolution of changes after treatment with intravenous anticoagulation, corticosteroids, antibiotics, plasma exchange, and intravenous immunoglobulin. Bill Giannakopoulos, and Steven A. Krilis Blood 2009;114:2020-2030 ©2009 by American Society of Hematology