Interneurons Scratch an Itch

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Interneurons Scratch an Itch Paula Juliana Seadi Pereira, Ethan A. Lerner  Neuron  Volume 82, Issue 3, Pages 503-505 (May 2014) DOI: 10.1016/j.neuron.2014.04.026 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Interneurons that Release Dynorphin Modulate Itch Neurons that respond to itch, cold, and noxious stimuli innervate and are modulated by B5-I interneurons that produce dynorphin. Capsaicin, mustard oil, and menthol activate TRPV1, TRPA1, and TRPM8, respectively. B5-I, inhibitory neurons that are a focus of the report to which this Preview is directed. GRPR, gastrin-releasing peptide receptor. Npra, natriuretic peptide receptor A is the receptor for the B-type natriuretic peptide BNP, also known as Nppb. Image modified and reproduced under CC-BY license: http://creativecommons.org/licenses/by/3.0/us/legalcode. Neuron 2014 82, 503-505DOI: (10.1016/j.neuron.2014.04.026) Copyright © 2014 Elsevier Inc. Terms and Conditions