Cardiac Structure and Ventricular–Vascular Function in Persons With Heart Failure and Preserved Ejection Fraction From Olmsted County, Minnesota by Carolyn.

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Presentation transcript:

Cardiac Structure and Ventricular–Vascular Function in Persons With Heart Failure and Preserved Ejection Fraction From Olmsted County, Minnesota by Carolyn S.P. Lam, Véronique L. Roger, Richard J. Rodeheffer, Francesca Bursi, Barry A. Borlaug, Steve R. Ommen, David A. Kass, and Margaret M. Redfield Circulation Volume 115(15):1982-1990 April 17, 2007 Copyright © American Heart Association, Inc. All rights reserved.

Figure 1. Schematic of group-averaged end-systolic pressure–volume relationship (ESPVR), where ESP=Ees(ESV−V0) (V0 is volume intercept). Figure 1. Schematic of group-averaged end-systolic pressure–volume relationship (ESPVR), where ESP=Ees(ESV−V0) (V0 is volume intercept). Solid lines represent the mean ESPVR; dotted lines, 95% CI for each group. For comparison of Ees (slope) between groups, *P<0.05 vs CON. Carolyn S.P. Lam et al. Circulation. 2007;115:1982-1990 Copyright © American Heart Association, Inc. All rights reserved.

Figure 2. Bar graphs of EDVI, indexed left atrial volume (LAVI), EDP, plasma brain natriuretic peptide (BNP), and derived τ by subject group. Figure 2. Bar graphs of EDVI, indexed left atrial volume (LAVI), EDP, plasma brain natriuretic peptide (BNP), and derived τ by subject group. Data are mean±SD. *P<0.05 vs CON; †P<0.05 vs HTN. Carolyn S.P. Lam et al. Circulation. 2007;115:1982-1990 Copyright © American Heart Association, Inc. All rights reserved.

Figure 3. Schematic of group-averaged EDPVR, where EDP=αEDVβ (α=curve-fitting constant, β=diastolic stiffness constant). Figure 3. Schematic of group-averaged EDPVR, where EDP=αEDVβ (α=curve-fitting constant, β=diastolic stiffness constant). Solid lines represent the mean EDPVR; dotted lines, 95% CI for each group. For comparison of EDVI20 between groups, *P<0.05 vs CON; † P<0.05 vs HTN. Carolyn S.P. Lam et al. Circulation. 2007;115:1982-1990 Copyright © American Heart Association, Inc. All rights reserved.