Exploring Membrane Structure and Function Research-Based, Interdisciplinary STEM Education (RISE)
Today’s Agenda: Introduction to the Cell Membrane Intermolecular Forces and Membrane Transport For Next Week: Read the papers provided and prepare a brief summary with two+ questions
The Fluid Mosaic Model of the Cell Membrane
Key Structural Component: The Phospholipid Think/ Pair/ Share: What do you notice about the structure of this molecule? Think/ Pair/ Share: What does this mean for the intermolecular forces between these molecules?
London Dispersion Forces
Dipole-Dipole Forces
Hydrogen Bonds Figure: 10-06-02UN Title: Hydrogen bonding Caption: Hydrogen bonds are also found between molecules of water and molecules of ammonia. They are defined as the attractive interaction between a hydrogen atom bonded to a very electronegative atom (O, N, or F) and an unshared electron pair on another electronegative atom.
Key Structural Component: The Phospholipid
Key Structural Component: A Mosaic of Proteins
A Quick Look at Protein Structure
A Quick Look at Protein Structure
Key Features of Membrane Proteins Think/ Pair/ Share: What must be true about the structure of proteins that span the cell membrane?
Visualizing the Cell Membrane: https://www.youtube.com/watch?v=LKN5sq5dtW4&list=PL13jH2BYL65_q5j1vBga32xNiYT57P5KC
Crossing the Cell Membrane What types of things does a cell need to get across its membrane? Of those things, which can cross freely?? Why?? What about everything else??
X Cell membranes are SELECTIVELY PERMEABLE O2, CO2, and other small, nonpolar molecules; and H2O large, polar molecules; ions such as H+, Na+, CI-, Ca++; X
Your Challenge: Use your understanding of protein structure to construct a model (drawing) of what a water channel in a cell membrane would look like, and how it would orient itself in a plasma membrane. Would such a channel need to be specific for water? If so, how could it accomplish this specificity?
For Next Week: Read the papers provided and prepare a brief summary with two+ questions