By: Jonathan Cookmeyer and Mehran Hazheer Tay Sachs Disease By: Jonathan Cookmeyer and Mehran Hazheer

Cause Chromosome 15 Protein hexosaminidase A (HEX A) GM2 gangliosides

Symptoms Red spot retina Motor/metal skills Paralysis Cramps Slurred speech Behavioral changes

Treatment None for Early/Juvenile Accommodating for muscle weakness Enzyme Therapy

Groups of people Ashkenazi Jewish French Canadian Cajun

For testing No cure Gets worse quickly Decreased amount of patients Blood test Prenatal testing

Against testing Prenatal testing Painful to mother Harm Fetus Miscarriage Deformity Infection