Periungual fibroma (Koenen tumors) as isolated sign of tuberous sclerosis complex with tuberous sclerosis complex 1 germline mutation Sven R. Quist,

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Presentation transcript:

Periungual fibroma (Koenen tumors) as isolated sign of tuberous sclerosis complex with tuberous sclerosis complex 1 germline mutation Sven R. Quist, MD, MSc, Ingolf Franke, MD, Christian Sutter, PhD, Claus R. Bartram, MD, Harald P. Gollnick, MD, Martin Leverkus, MD Journal of the American Academy of Dermatology Volume 62, Issue 1, Pages 159-161 (January 2010) DOI: 10.1016/j.jaad.2009.01.021 Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Isolated Koenen tumors as a sign of tuberous sclerosis complex. Multiple subungual and periungual fibromas. Skin-colored erythematous papules and tumors are seen on the right (A) and left (B) hand, the right (C) and left (D) foot, the left thumbnail (E), and the fourth digit of the left hand (F). Journal of the American Academy of Dermatology 2010 62, 159-161DOI: (10.1016/j.jaad.2009.01.021) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Periungual fibroma of the thumbnail (Koenen tumor) (A). Histopathology reveals extensive dermal fibrosis (B) with multiple ectatic vessels (C). (Hematoxylin–eosin stain.) Journal of the American Academy of Dermatology 2010 62, 159-161DOI: (10.1016/j.jaad.2009.01.021) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions