SDF-1/CXCR4 expression in head and neck cancer and outcome after postoperative radiochemotherapy Chiara De-Colle, David Mönnich, Stefan Welz, Simon Boeke,

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SDF-1/CXCR4 expression in head and neck cancer and outcome after postoperative radiochemotherapy Chiara De-Colle, David Mönnich, Stefan Welz, Simon Boeke, Bence Sipos, Falko Fend, Paul-Stefan Mauz, Inge Tinhofer, Volker Budach, Jehad Abu Jawad, Martin Stuschke, Panagiotis Balermpas, Claus Rödel, Anca-Ligia Grosu, Amir Abdollahi, Jürgen Debus, Christine Bayer, Claus Belka, Steffi Pigorsch, Stephanie E. Combs, Fabian Lohaus, Annett Linge, Mechthild Krause, Michael Baumann, Daniel Zips, Apostolos Menegakis Clinical and Translational Radiation Oncology Volume 5, Pages 28-36 (August 2017) DOI: 10.1016/j.ctro.2017.06.004 Copyright © 2017 The Authors Terms and Conditions

Fig. 1 Representative images of SDF-1 immunofluorescent stained tumour sections. (A) Membrane staining (score 3). (B) Intracellular staining (score 2). (C) Negative staining (score 0). SDF-1 is shown in green, DAPI in blue. Similar staining patterns and intensities were observed for CXCR4. Original image magnification: 400×. Clinical and Translational Radiation Oncology 2017 5, 28-36DOI: (10.1016/j.ctro.2017.06.004) Copyright © 2017 The Authors Terms and Conditions

Fig. 2 A–D: Kaplan-Meier curves for locoregional tumour control in all patients (A and C) and patients with HPV16 DNA negative tumours only (B and D) according to the SDF-1 and CXCR4 intracellular expression. Clinical and Translational Radiation Oncology 2017 5, 28-36DOI: (10.1016/j.ctro.2017.06.004) Copyright © 2017 The Authors Terms and Conditions