Association of blood lipids with AF

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Presentation transcript:

Association of blood lipids with AF Association of blood lipids with AF. Cohort-specific and combined HRs and 95% CIs associated with a 1SD increment in blood lipids (total cholesterol: 35 mg/dL; HDLc: 15 mg/dL; LDLc: 35 mg/dL; triglycerides: 65 mg/dL). Association of blood lipids with AF. Cohort-specific and combined HRs and 95% CIs associated with a 1SD increment in blood lipids (total cholesterol: 35 mg/dL; HDLc: 15 mg/dL; LDLc: 35 mg/dL; triglycerides: 65 mg/dL). P values are from heterogeneity tests. Cohort-specific estimates are combined using fixed-effects meta-analysis. Results from Cox proportional hazards models adjusted for age, sex, race or ethnicity (only in MESA), study site (only in MESA), education, height, body mass index, smoking status, alcohol drinking, physical activity, systolic and diastolic blood pressure, use of antihypertensive medication, diabetes, C-reactive protein, and loge(N-terminal prohormone of B-type natriuretic peptide) (in MESA) or loge(B-type natriuretic peptide) (in the FHS). FHS indicates Framingham Heart Study; HDLc, high-density lipoprotein cholesterol; HR, hazard ratio; LDLc, low-density lipoprotein cholesterol; MESA, Multi-Ethnic Study of Atherosclerosis. Alvaro Alonso et al. J Am Heart Assoc 2014;3:e001211 © 2014 Alvaro Alonso et al.