Nens220, Lecture IX Oscillations, resonance, synchrony, biophysically-based neuronal networks John Huguenard.

Slides:

Advertisements

Similar presentations

Rhythms in the Nervous System : Synchronization and Beyond Rhythms in the nervous system are classified by frequency. Alpha 8-12 Hz Beta Gamma

Advertisements

Slow oscillation, Fast oscillation, and its interactions

The abrupt transition from theta to hyper- excitable spiking activity in stellate cells from layer II of the medial entorhinal cortex Horacio G. Rotstein.

Customization of coherence analysis by relaxing its iso-frequency constraint Pooya Pakarian 1 & Arash Hadipour Niktarash 2 1 Program in Neural Computation,

Synchrony in Neural Systems: a very brief, biased, basic view Tim Lewis UC Davis NIMBIOS Workshop on Synchrony April 11, 2011.

Salva Sadeghi December 1 st,  Definition of Spike-and-Wave Patterns  SWD Observations and Characteristics  Thalamocortical Circuits  Experimental.

Neural Coding 4: information breakdown. Multi-dimensional codes can be split in different components Information that the dimension of the code will convey.

Research Plans Computational Neuroscience Jutta Kretzberg University of Antwerp

Neuromodulation - signal-to-noise - switching - burst/single spike - oscillations.

Dynamic changes of somatosensory evoked potentials in rats and humans during wake-sleep states Institute of Cognitive Science, National Cheng Kung University.

Epilepsy: Error of Scales? Ann Arbor, MI 2007 Theoden Netoff University of Minnesota, BME.

EE141 1 Broca’s area Pars opercularis Motor cortexSomatosensory cortex Sensory associative cortex Primary Auditory cortex Wernicke’s area Visual associative.

SME Review - September 20, 2006 Neural Network Modeling Jean Carlson, Ted Brookings.

Functional Brain Signal Processing: Current Trends and Future Directions Kaushik Majumdar Indian Statistical Institute Bangalore Center

Basic Mechanisms of Seizure Generation John G.R. Jefferys Marom BiksonPremysl Jiruska John FoxMartin Vreugdenhil Jackie DeansWei-Chih Chang Joseph CsicsvariXiaoli.

Matt Mehne, USC Brain Project 1 USC Brain Project Matt Mehne – Progress Update – May 15, 2007 Modeling Action Selection in the Parkinsonian Basal Ganglia.

Karlijn van Aerde. Two independent cortical subnetworks control spike timing of layer 5 pyramidal neurons during dynamic β oscillation shifts Karlijn.

The Diencephalon Basic Neuroscience James H. Baños, Ph.D.

Sparsely Synchronized Brain Rhythms in A Small-World Neural Network W. Lim (DNUE) and S.-Y. KIM (LABASIS)

The brain is impossibly complicated - if it were simple enough to understand, we'd be too simple to understand it. - Lyall Watson.

Correlation-Induced Oscillations in Spatio-Temporal Excitable Systems Andre Longtin Physics Department, University of Ottawa Ottawa, Canada.

Dana Ballard - University of Rochester1 Distributed Synchrony: a model for cortical communication Madhur Ambastha Jonathan Shaw Zuohua Zhang Dana H. Ballard.

Normal and pathological oscillatory communication in the brain

TEMPLATE DESIGN © In analyzing the trajectory as time passes, I find that: The trajectory is trying to follow the moving.

Brain Rhythms: key questions  Coordination of processing across space  Coherence in perception, e.g. synchrony & binding, cognitive moment, causation/objects.

Week 14 The Memory Function of Sleep Group 3 Tawni Voyles Alyona Koneva Bayou Wang.

Measuring brain activity Blood flow fMRI, PET, NIRS Electrical activity EEG.

Are worms more complex than humans? Rodrigo Quian Quiroga Sloan-Swartz Center for Theoretical Neurobiology. Caltech.

Rhythms and Cognition: Creation and Coordination of Cell Assemblies Nancy Kopell Center for BioDynamics Boston University.

Review – Objectives Transitioning 4-5 Spikes can be detected from many neurons near the electrode tip. What are some ways to determine which spikes belong.

Ch 9. Rhythms and Synchrony 9.7 Adaptive Cooperative Systems, Martin Beckerman, Summarized by M.-O. Heo Biointelligence Laboratory, Seoul National.

Nens220, Lecture 11 Introduction to Realistic Neuronal Networks John Huguenard.

Biological Modeling of Neural Networks: Week 10 – Neuronal Populations Wulfram Gerstner EPFL, Lausanne, Switzerland 10.1 Cortical Populations - columns.

Nens220, Lecture 6 Interneuronal communication John Huguenard.

Brain circuits for spatial cognition Nitin Gupta 5 November, 2014 All of this presentation is based on work performed by others.

Richard Tomsett1,2 Marcus Kaiser1,3,4

Memory Systems Hippocampus.

Theta, Gamma, and Working Memory

CONVULSION & EPILEPSY Dr. Kifah Alubaidy.

NATURE NEUROSCIENCE 2007 Coordinated memory replay in the visual cortex and hippocampus during sleep Daoyun Ji & Matthew A Wilson Department of Brain.

Cycle 7: Thalamocortical Oscillations

How and why neurons fire

Neuronal Networks So far: the building blocks of neurons/networks

Modulation of local and long-distance

Jaeseung Jeong, Ph.D Department of Bio and Brain Engineering, KAIST

Basal ganglia function

Nens220, Lecture 5 Beyond Hodgkin-Huxley

Presented by Rhee, Je-Keun

Information Processing by Neuronal Populations

Mircea Steriade, Igor Timofeev Neuron

H-Current Neuron Volume 21, Issue 1, Pages 9-12 (July 1998)

Dissecting the Dynamics of Corticothalamic Feedback

Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to Generate Epilepsy? Mark P. Beenhakker, John R. Huguenard Neuron

Tuning Out the Noise: Limbic-Auditory Interactions in Tinnitus

Synchrony & Perception

Presented by: Rezvan Kianifar January 2009

Chapter 49 Nervous Systems.

P. Michelle Fogerson, John R. Huguenard Neuron

Computational Models of Grid Cells

GABAergic Interneurons Shape the Functional Maturation of the Cortex

Amygdala Inhibitory Circuits and the Control of Fear Memory

Synaptic Plasticity, Engrams, and Network Oscillations in Amygdala Circuits for Storage and Retrieval of Emotional Memories Marco Bocchio, Sadegh Nabavi,

Systems neuroscience: The slowly sleeping slab and slice

Grid Cells and Neural Coding in High-End Cortices

Remembering the Caribbean

In vitro networks: cortical mechanisms of anaesthetic action

BASAL NUCLEI. BASAL NUCLEI Basal Ganglia Functions Compare proprioceptive information and movement commands. Sequence movements. Regulate muscle tone.

Rapid Neocortical Dynamics: Cellular and Network Mechanisms

Associational cortex introduction

Week 7a: Action Potential Part 2: Spike patterning

Presentation transcript:

Nens220, Lecture IX Oscillations, resonance, synchrony, biophysically-based neuronal networks John Huguenard

Neuronal oscillations: functions Sleep Generate activity that is independent of sensory input May play roles in memory consolidation or reprioritization. Spindles, delta, sharp-wave ripple complexes Awake behavior Exploration – theta Sensory binding & attention – gamma Sensory discrimination – olfaction in insects Pathology Epilepsy Parkinson’s disease

Neuronal oscillations: mechanisms Intrinsic neuronal properties Resonance Network feedback Can interact with neuronal properties to reinforce or cancel network responses Dynamics Initiation Propagation Termination

Determining neuronal resonance Gutfreund et al, J Physiol. 483:621, 1995

Resonance and coding space “Grid” cells in in entorhinal cortex part of space encoding network. Hafting .. Moser Nature 436:801, 2005

Resonance and coding space “Grid” cells in in entorhinal cortex part of space encoding network. Alonso & Llinas Nature 342:172, 1989 Giocomo et al Science, 315:1719, 2007

Resonance and coding space “Grid” cells in in entorhinal cortex part of space encoding network. Giocomo et al Science, 315:1719, 2007

Resonance in thalamic relay neurons

Thalamic reticular cells: Intrinsic oscillators Avanzini et al J Physiol. 416:111, 1989

Thalamic reticular cells Mechanisms of intrinsic oscillations Wallenstein, Biophys J 66:978, 1994

K complex and spindles in early sleep Incomplete syncrony. Note time of spindle occurrence at different leads compare this to swd Courtesy of K. Graber

The thalamocortical system Corpus striatum Sensory relay Sleep oscillations A RE VA VL M VP LP Pu LGN MGN Drawing from Dr. Wolfgang Klimesch

Intracellular studies of spindles in vivo Incomplete synchrony, sparseness, also seen in vitro, higher synchrony seen during seizures Roaming cortical activation, perhaps semi-random to reactivate cortical circuits during slow wave sleep Modified from Steriade and Llinás. Physiol.Rev. 68:649-742, 1988.

Thalamus: Inhibitory network oscillations + Cx

Modeling a large scale thalamocortical network Destexhe (1998) J. Neurosci. 18, 9099-9111.

Modeling a large scale thalamocortical network Destexhe (1998) J. Neurosci. 18, 9099-9111.

Modeling a large scale thalamocortical network Destexhe (1998) J. Neurosci. 18, 9099-9111.

250 pA 2.5 ms 250 pA Fran Shen

Dynamic-Clamp: Artificial Autaptic IPSCs Based on Fuhrmann, et al. J Neurophysiol 87: 140–148, 2002