Human Pedigree-Based Quantitative-Trait–Locus Mapping: Localization of Two Genes Influencing HDL-Cholesterol Metabolism Laura Almasy, James E. Hixson, David L. Rainwater, Shelley Cole, Jeff T. Williams, Michael C. Mahaney, John L. VandeBerg, Michael P. Stern, Jean W. MacCluer, John Blangero The American Journal of Human Genetics Volume 64, Issue 6, Pages 1686-1693 (June 1999) DOI: 10.1086/302425 Copyright © 1999 The American Society of Human Genetics Terms and Conditions
Figure 1 Multipoint linkage analysis of HDL2a-UC on chromosomes 8 (A) and 15 (B). The American Journal of Human Genetics 1999 64, 1686-1693DOI: (10.1086/302425) Copyright © 1999 The American Society of Human Genetics Terms and Conditions
Figure 2 Joint two-locus LOD scores for HDL2a-UC on chromosomes 8 and 15. The American Journal of Human Genetics 1999 64, 1686-1693DOI: (10.1086/302425) Copyright © 1999 The American Society of Human Genetics Terms and Conditions
Figure 3 LOD scores for concentration of UC, in 0.1-nm HDL particle–size increments, at multipoint HDL2a-UC linkage peaks on chromosomes 8 (A) and 15 (B) and for proportion of UC, in 0.1-nm HDL particle–size increments, at the same chromosome 15 location (C). The American Journal of Human Genetics 1999 64, 1686-1693DOI: (10.1086/302425) Copyright © 1999 The American Society of Human Genetics Terms and Conditions