How I treat extramedullary myeloma

Slides:



Advertisements
Similar presentations
14 Identify the fibers coursing at the blue arrow.
Advertisements

Kara Penney Bone Cancer. Osteosarcoma Chondrosarcoma The Ewing Sarcoma Family of Tumors (ESTFs) Types of Bone Cancer.
New criteria for response assessment: role of minimal residual disease in multiple myeloma by Bruno Paiva, Jacques J. M. van Dongen, and Alberto Orfao.
Pathogenesis beyond the cancer clone(s) in multiple myeloma by Giada Bianchi, and Nikhil C. Munshi Blood Volume 125(20): May 14, 2015 ©2015 by.
Multiple Myeloma: 18F-FDG-PET/CT and Diagnostic Imaging
IFM/DFCI 2009 Trial: Autologous Stem Cell Transplantation (ASCT) for Multiple Myeloma (MM) in the Era of New Drugs Phase III study of lenalidomide/bortezomib/dexamethasone.
Neuroretinitis in patients with multiple sclerosis
Hugo J.A. Adams, Rutger A.J. Nievelstein, Thomas C. Kwee  Blood Reviews 
From: Permanent Loss of Cervical Spinal Cord Function Associated with Interscalene Block Performed under General Anesthesia Anesthes. 2000;93(6):
Donald R. Murphy, DC, Nicholas J. Morris, DC 
PET, CT, and MRI with Combidex for mediastinal staging in non-small cell lung carcinoma  Kemp H Kernstine, MD, PhD, William Stanford, MD, Brian F Mullan,
How I treat multiple myeloma in younger patients
Prophylactic human granulocyte colony-stimulating factor after induction therapy in pediatric acute myeloid leukemia by Thomas Lehrnbecher, Martin Zimmermann,
Comparison of 200 mg/m2 melphalan and 8 Gy total body irradiation plus 140 mg/m2 melphalan as conditioning regimens for peripheral blood stem cell transplantation.
Jenny Dave, MS, Mark A. Ahlman, MD, Benjamin N. Lockshin, MD, David A
by James O. Armitage, and Dan L. Longo
Dasatinib induces complete remission in a patient with primary cerebral involvement of B-cell chronic lymphocytic leukemia failing chemotherapy by Georg.
Figure 2 New functional imaging techniques in lymphoma
A Clinical Evaluation of the International Lymphoma Study Group Classification of Non-Hodgkin's Lymphoma Blood Volume 89(11): June 1, 1997 ©1997.
by Thomas S. Uldrick, and Richard F. Little
T-cell epitopes within the complementarity-determining and framework regions of the tumor-derived immunoglobulin heavy chain in multiple myeloma by Lotta.
Reversible posterior leukoencephalopathy syndrome and silent cerebral infarcts are associated with severe acute chest syndrome in children with sickle.
Transplants for the elderly in myeloma
How I treat elderly patients with myeloma
Radiofrequency ablation of lymphoma
by Thomas Rasmussen, Linda Jensen, Lone Honoré, and Hans Erik Johnsen
Darwinian evolution and tiding clones in multiple myeloma
An Unusual Cause of Abdominal Pain in Sickle Cell Disease
Parasternal mass Blood Volume 113(6): February 5, 2009
Leptomeningeal and Medullary Response to Second-Line Erlotinib in Lung Adenocarcinoma  Mathilde Wagner, MD, Benjamin Besse, MD, Corinne Balleyguier, MD,
Vanessa Correa, MD, Janine Vintch, MD, Charles Lanks, MD  CHEST 
by Eli L. Diamond, Omar Abdel-Wahab, Benjamin H
Young Adult Male in a Coma
by Sabah Sallah, and Jim Y. Wan
Primary testicular lymphoma
Blocking VWF platelet binding to treat TTP
Figure 3 Example of venous narrowing
Patient with cholesteatoma on the right and chronic otitis media without cholesteatoma on the left. Patient with cholesteatoma on the right and chronic.
Figure 4 New PET radiotracers in lymphoma
Donald R. Murphy, DC, Nicholas J. Morris, DC 
Brain MRI scans for the patient.
Phase II Study of Risk-Adapted Therapy of Newly Diagnosed, Aggressive Non-Hodgkin Lymphoma Based on Midtreatment FDG-PET Scanning  Yvette L. Kasamon,
MRI in sickle cell disease.
Submassive pulmonary embolism in patient 2.
Figure 2 Example of venous narrowing
Kamal Kant Singh Abbi, Junting Zheng, Sean M
Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma  Dharshan Sivaraj, Michael.
The Incidental Pancreatic Cyst on Abdominal Computerized Tomography Imaging: Diagnosis and Management  William R. Brugge  Clinical Gastroenterology and.
CD34-Selected Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Relapsed, High-Risk Multiple Myeloma  Eric Smith, Sean M. Devlin, Satyajit.
Daratumumab in Combination with Carfilzomib and Dexamethasone in Patients (pts) with Relapsed Multiple Myeloma (MMY1001): An Open-Label, Phase 1b Study.
Clinical Challenges in the Patient With Relapsed Multiple Myeloma
Acute and chronic dissections of the abdominal aorta: Clinical features and treatment  Jean-Pierre Becquemin, MD, Philippe Deleuze, MD, Jacques Watelet,
Fig F-FGln shows uptake in human gliomas undergoing progression.
Impact of post-ASCT maintenance therapy on outcomes in patients with newly diagnosed multiple myeloma in Connect MM by Sundar Jagannath, Rafat Abonour,
Positron emission tomography/computed tomography scans showed a mass lesion. a) Areas of cavitation were noted in the left lower lobe, encasing the segmental.
Venetoclax Monotherapy for Relapsed/Refractory Multiple Myeloma: Safety and Efficacy Results from a Phase I Study by Shaji Kumar, Ravi Vij, Jonathan L.
Coronal FLAIR images (A–C) document decreasing left hippocampal mass effect and signal intensity over 5-year period (black arrowhead). Coronal FLAIR images.
Figure Rapid progression of lesions after natalizumab treatment(A) MRI from February Rapid progression of lesions after natalizumab treatment(A)
Fig. 1. Brain imaging before surgery
Typical supratentorial right frontal cPML in an HIV-positive patient.
Contrast-enhancing lesions on CT scans (A–D) in 4 patients with AIDS-related PCNSL. Note irregularly enhancing lesions in the right parietal lobe (A),
Sagittal reconstruction of a CT scan of a 6-year-old boy (patient 3) after a fall (GCS = 15) demonstrates an REH (thick white arrow), which causes mild.
Serial imaging before and after immunotherapy among patients with MDM2/4 amplifications (N = 6). Serial imaging before and after immunotherapy among patients.
Axial contrast-enhanced CT demonstrates a myocutaneous fat flap (white arrow) used for reconstruction following resection of a squamous cell carcinoma.
by Lapo Alinari, and Kristie A. Blum
Initial treatment of CLL: integrating biology and functional status
A, Axial T2-weighted image (3500/90/2) shows a well-defined deep right occipital white matter lesion (asterisk) and a subcortical linear hyperintensity.
Figure 7b. Complications of pancreatitis mimicking a pancreatic tumor
Contrast-enhanced axial CT scan through the larynx with soft-tissue reconstruction demonstrates complete ossification of the thyroid (white arrow) and.
A left centrum semiovale lesion in a 30-year-old woman with relapsing-remitting MS; the time lapse between 3T and 7T scans was 6 months. A left centrum.
Presentation transcript:

How I treat extramedullary myeloma by Cyrille Touzeau, and Philippe Moreau Blood Volume 127(8):971-976 February 25, 2016 ©2016 by American Society of Hematology

MRI. MRI. MRI (T1 weighted) showing an occipital mass with leptomeningeal involvement (A, white arrow) and multiple posterior medullary lesions (B, white arrows), in a relapsed MM patient who developed progressive ataxia. Cyrille Touzeau, and Philippe Moreau Blood 2016;127:971-976 ©2016 by American Society of Hematology

PET-CT scan. PET-CT scan. PET-CT scan (A) demonstrating increased FDG avidity of the pancreas (B, arrows) in an MM patient who developed epigastric pain during maintenance therapy. Cyrille Touzeau, and Philippe Moreau Blood 2016;127:971-976 ©2016 by American Society of Hematology