Effects of Surgical Revascularization on Cerebral Oxygen Metabolism in Patients With Moyamoya Disease by Satoshi Kuroda, Daina Kashiwazaki, Kenji Hirata,

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Effects of Surgical Revascularization on Cerebral Oxygen Metabolism in Patients With Moyamoya Disease by Satoshi Kuroda, Daina Kashiwazaki, Kenji Hirata, Tohru Shiga, Kiyohiro Houkin, and Nagara Tamaki Stroke Volume 45(9):2717-2721 August 25, 2014 Copyright © American Heart Association, Inc. All rights reserved.

Radiological findings of a 8-year-old girl who developed transient motor aphasia. Radiological findings of a 8-year-old girl who developed transient motor aphasia. A, Preoperative T2-weighted MRI revealed no parenchymal lesion in the brain. B, Preoperative left internal carotid angiography revealed a marked stenosis of the left carotid fork and the development of basal moyamoya vessels. C, Preoperative positron emission tomographic (PET) scans showed cerebral blood flow (CBF) decrease, cerebral blood volume (CBV) increase, cerebral metabolic rate for oxygen (CMRO2) decrease, and oxygen extraction fraction (OEF) elevation in the left cerebral hemisphere. Note a marked reduction of CMRO2 in the left cerebral hemisphere (arrows). D, Postoperative PET scans performed 4 months after surgery revealed a normalization of all of 4 PET parameters. Note a normalization of CMRO2 in the left cerebral hemisphere (arrows). Satoshi Kuroda et al. Stroke. 2014;45:2717-2721 Copyright © American Heart Association, Inc. All rights reserved.