Metastasis of colon adenocarcinoma to the mandible: A case report

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Metastasis of colon adenocarcinoma to the mandible: A case report Ayako Kameta, Takaaki Oda, Ichiro Ogura, Junya Ono, Yoriaki Kanri, Yasuo Okada, Makoto Tsuchimochi  Oral Science International  Volume 14, Issue 1, Pages 22-25 (January 2017) DOI: 10.1016/S1348-8643(16)30023-4 Copyright © 2016 Terms and Conditions

Fig. 1 Panoramic radiograph showing a radiolucency with ill-defined margin in the right mandible. Oral Science International 2017 14, 22-25DOI: (10.1016/S1348-8643(16)30023-4) Copyright © 2016 Terms and Conditions

Fig. 2 (a) Axial CT shows an osteolytic lesion with the destruction of buccal cortex in the right mandible. (b) The buccal cortex shows a moth-eaten appearance on a coronal reformatted CT. (c) Sagittal reformatted CT shows the lesion affecting the mandibular canal. (d) Three-dimensional reconstructed CT shows the lesion affecting the mental foramen. Oral Science International 2017 14, 22-25DOI: (10.1016/S1348-8643(16)30023-4) Copyright © 2016 Terms and Conditions

Fig. 3 MRI showing a round-shaped homogeneous intensity mass expanding from the mandible. (a) The lesion shows low intensity on a T1-weighted image. (b) The lesion shows high intensity on a T2-weighted image. (c) The lesion shows high intensity on a STIR image. Oral Science International 2017 14, 22-25DOI: (10.1016/S1348-8643(16)30023-4) Copyright © 2016 Terms and Conditions

Fig. 4 Microscopic findings. (a) Histopathological findings of the surgical specimen of the ascending colon (primary site). Moderately differentiated adenocarcinoma was observed. Glands were irregular and tortuous. The nuclei were elongated and stratified. (b) Histopathological findings of the biopsy specimen of the right mandible (metastatic site). Adenocarcinoma similar to the primary tumor and mandibular bone spicules (*) were observed. Bars: 100μm. Oral Science International 2017 14, 22-25DOI: (10.1016/S1348-8643(16)30023-4) Copyright © 2016 Terms and Conditions