Shigella-specific serum IgG and IgA endpoint titers in guinea pigs immunized intranasally with S. flexneri 2a InvaplexNAT or InvaplexAR. Shigella-specific.

Slides:

Advertisements

Similar presentations

Figure 4. Reduced Ab production in Egr1-/- mice

Advertisements

Interleukin-5–producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy by Frédéric Van Gool, Ari B. Molofsky, Malika.

Volume 8, Issue 3, Pages (September 2003)

Anna Tinnert, Annika Hamlet, Ann-Mari Svennerholm

Volume 15, Issue 2, Pages (February 2007)

by Norman Nausch, Ioanna E

Metalloproteinases Are Involved in Lipopolysaccharide– and Tumor Necrosis Factor-–Mediated Regulation of CXCR1 and CXCR2 Chemokine Receptor Expression.

Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells by Wuding Zhou, Hetal Patel, Ke Li, Qi Peng, Marie-Bernadette.

Increased survival is a selective feature of human circulating antigen-induced plasma cells synthesizing high-affinity antibodies by Inés González-García,

Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy by Fumihiko Tsushima, Sheng Yao, Tahiro Shin, Andrew Flies, Sarah.

Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation by Eric Boilard, Guillaume Paré, Matthieu Rousseau, Nathalie.

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of.

Volume 22, Issue 7, Pages (July 2014)

Loss of vimentin in B cells impairs antibody response in vivo.

FMDV-specific IgG, IgG1, and IgG2 in sera of guinea pigs (n = 6/group) immunized on days 1 and 21 by intramuscular injection of FMDV antigens (type O)

HA-specific Abs in serum 14 d after a single vaccination with the various targeted DNA vaccines. HA-specific Abs in serum 14 d after a single vaccination.

A single DNA vaccination of C57BL/6 mice induced Ab responses of IgG1 and/or IgG2c subclass. A single DNA vaccination of C57BL/6 mice induced Ab responses.

Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice by Julie Lang, Bicheng Zhang, Margot Kelly, Jacob.

Virus-specific serum antibody response of BALB/c mice to DNA prime followed by VRP boost. Virus-specific serum antibody response of BALB/c mice to DNA.

Protection from influenza virus challenge.

FMD VP1-specific IgG, IgG1, and IgG2 in sera of guinea pigs (n = 6/group) immunized on days 1 and 21 by intramuscular injection of FMDV antigens (type.

Anna Tinnert, Annika Hamlet, Ann-Mari Svennerholm

Robust adaptive immune response against Babesia microti infection marked by low parasitemia in a murine model of sickle cell disease by Woelsung Yi, Weili.

Detection of CSFV-specific antibodies in immunized/challenged pigs using blocking ELISA. Groups of pigs (n = 5) were inoculated with different doses of.

Virus-specific serum antibody response of BALB/c mice to DNA prime followed by VRP boost. Virus-specific serum antibody response of BALB/c mice to DNA.

Titration of antibiotic perturbations results in altered community structures and C. difficile colonization resistance. Titration of antibiotic perturbations.

Categorization of the top 200 N

by Kalpana Parvathaneni, and David W. Scott

Comparison of relative activity of Adjuplex and other commonly used adjuvants. Comparison of relative activity of Adjuplex and other commonly used adjuvants.

The virulence of Candida species in Galleria mellonella larvae at 37°C is species specific. The virulence of Candida species in Galleria mellonella larvae.

Characterization of cell stages and morphologies under the culture conditions used in this study. Characterization of cell stages and morphologies under.

Coexpression of the adjuvant mmCT with chromosomal RΔ-CTB attenuates the immune response to CTB. (A) Genotype of an O139 serotype vaccine strain in which.

Longevity of mucosal and systemic antibody responses induced by pulmonary vaccination. Longevity of mucosal and systemic antibody responses induced by.

Phenotype of rTT.C-specific plasma blasts.

Volume 19, Issue 3, Pages (March 2011)

Collagen accumulation is reduced with UK

Box plots showing the relative difference in distribution of mtDNA copy number per cell between patients with ESRD and healthy control subjects frequency.

Chromosomally expressed RΔ-CTB is poorly immunogenic.

Antibody reactivity against HA1 proteins after vaccination.

Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp for each of 13 serotypes. Dynamic ranges of anti-PnPS IgG Reference standard serum 007sp.

Dynamic light scattering (DLS) analysis of S

Pulmonary vaccination induces a long-term immune memory response to antigen challenge. Pulmonary vaccination induces a long-term immune memory response.

NK cell function of spleen MNCs (A) and NK cell frequencies in the ileum, duodenum, and spleen (B) of protein-deficient and -sufficient HIFM/HRV-infected.

Bar graph of the number of averaged activated voxels (normalized to control values), as defined by increases in lactate concentration in the left frontal.

Superspacers shared between viral strains.

OVA-specific and InvaplexNAT-specific serum IgG endpoint titers in mice after intranasal immunization with OVA alone or OVA combined with InvaplexAR, InvaplexNAT,

Prime and boosts with PBK001 vaccine provided 100% protection with low bacterial burden in organs. Prime and boosts with PBK001 vaccine provided 100% protection.

Blood Tfr cells do not show specialized humoral regulatory capacity.

Transgenic c-Maf mediates upregulation of type 2 cytokines in NOD CD4, but not CD8, cells. Transgenic c-Maf mediates upregulation of type 2 cytokines in.

Anti-DNA Abs were not affected by the deletion of GCs in pristane-induced lupus model. Anti-DNA Abs were not affected by the deletion of GCs in pristane-induced.

Increased autoantibodies in Bcl6FC mice.

Increased anti-DNA Abs in 2KO-Bcl6TC mice.

Low pH alters Ras1 localization and its activation state, but these changes are not responsible for the effect of pH on morphology. Low pH alters Ras1.

by Joan B. Mannick, Melody Morris, Hans-Ulrich P

Intranasal immunization of mice with S

The contributions of anti-Ad antibody and T-cell responses to viral clearance in tumor and antitumor efficacy of Ad5 therapy. The contributions of anti-Ad.

Analysis of PHO1 Expression by RT-qPCR in the pru1 Mutant, Complementation Lines (COM5 and COM7), and Wild-type Plants during Pi Starvation. Analysis of.

Basilar artery diameter measured with CTA in the delayed stage of SAH

X-tile analysis of survival data from the SEER registry reveals a continuous distribution based on tumor size and node number, and a U-shaped distribution.

LPS-induced TNF-α secretion from differentiated and undifferentiated THP-1 cells. LPS-induced TNF-α secretion from differentiated and undifferentiated.

Fig. 6 Multivalent DNA vaccine and protein antigen delivery by T4-AAV nanoparticles. Multivalent DNA vaccine and protein antigen delivery by T4-AAV nanoparticles.

RTA-specific serum IgG antibody titers and TNA in mice immunized with RiVax or RVEc. RTA-specific serum IgG titers after the second (A) or third (B) immunizations.

Increase in proliferation and activation of immune cells in peripheral blood after NKTR-214 treatment. Increase in proliferation and activation of immune.

Relationships between the AI in the subacute stage and neurologic state. Relationships between the AI in the subacute stage and neurologic state. No significant.

Intratumoral changes in critical lymphocyte populations and numbers after NKTR-214 treatment. Intratumoral changes in critical lymphocyte populations and.

B- and T-cell activity induced by immunization.

Regulation of antibacterial B cell responses in the peritoneal cavity via MyD88 signaling in FRCs. Regulation of antibacterial B cell responses in the.

CD38 regulates tumor growth and metastasis by adenosine-mediated CD8+ T-cell suppression. CD38 regulates tumor growth and metastasis by adenosine-mediated.

In the absence of TLR5 and inflammasome recognition, FliC’s D2/D3 domains are essential for secondary IgG1 and IgG2c anti-flagellin responses. In the absence.

Fig. 3 Evaluation of PTMAO immunogenicity.

Presentation transcript:

Shigella-specific serum IgG and IgA endpoint titers in guinea pigs immunized intranasally with S. flexneri 2a InvaplexNAT or InvaplexAR. Shigella-specific serum IgG and IgA endpoint titers in guinea pigs immunized intranasally with S. flexneri 2a InvaplexNAT or InvaplexAR. Groups of guinea pigs (n = 6/group) were immunized intranasally on days 0, 14, and 28. Dose amounts of S. flexneri 2a InvaplexNAT and S. flexneri 2a InvaplexAR are indicated on the x axis. Guinea pigs were challenged on day 49 with S. flexneri 2a strain 2457T. Blood was collected on days 0, 28, 40, and 63 and analyzed by ELISA for anti-S. flexneri 2a LPS (top panels) or IpaB (middle panels) or IpaC (bottom panels) serum IgG (left panels) and IgA (right panels) endpoint titers. The mean endpoint titer + 1 standard error of the mean on day 40 is plotted, and significant differences (two-way analysis of variance; P < 0.05) between dose-matched groups are indicated with an asterisk. K. Ross Turbyfill et al. mSphere 2018;3:e00583-17 ©2018 by American Society for Microbiology