Why not the liver instead of the kidney?

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Why not the liver instead of the kidney? by Joachim Fandrey Blood Volume 120(9):1760-1761 August 30, 2012 ©2012 by American Society of Hematology

Kidneys in renal insufficiency fail to produce erythropoietin (EPO). Kidneys in renal insufficiency fail to produce erythropoietin (EPO). Intravenous injection of lipid nano particles (LNPs) containing siRNA against EglNs activate hepatic EPO synthesis and stimulate erythropoiesis. Professional illustration by Kenneth X. Probst. Joachim Fandrey Blood 2012;120:1760-1761 ©2012 by American Society of Hematology