The Gene for Glycogen-Storage Disease Type 1b Maps to Chromosome 11q23

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The Gene for Glycogen-Storage Disease Type 1b Maps to Chromosome 11q23 Borhane Annabi, Brian C. Mansfield, Hisayuki Hiraiwa, Ke-Jian Lei, Tsuneyuki Ubagai, Mihael H. Polymeropoulos, Shimon W. Moses, Ruti Parvari, Eli Hershkovitz, Hanna Mandel, Moshe Fryman, Janice Yang Chou The American Journal of Human Genetics Volume 62, Issue 2, Pages 400-405 (February 1998) DOI: 10.1086/301727 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 1 Pedigrees of the nine GSD-1b families used in the linkage study. The haplotypes in loci D11S1340, D11S1998, D11S939, D11S1356, D11S4104, D11S1341, D11S976, D11S614, and D11S4129 are given for each genotyped individual. Blackened symbols represent affected individuals, and unblackened symbols represent unaffected individuals. Lack of homozygosity—observed in individuals V-4 and V-5, in family 1, for marker D11S1340, and in individual IV-3, in family 2, for marker D11S4129—is indicated by an arrow. The American Journal of Human Genetics 1998 62, 400-405DOI: (10.1086/301727) Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 2 The best-supported order and sex-averaged distances (in cM) between the markers showing linkage to the GSD-1b locus. The IL-10 receptor, Na/K-γATPase, and ALL-1 genes mapping to this region are shown. The American Journal of Human Genetics 1998 62, 400-405DOI: (10.1086/301727) Copyright © 1998 The American Society of Human Genetics Terms and Conditions