Volume 382, Issue 9887, Pages (July 2013)

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Volume 382, Issue 9887, Pages 129-137 (July 2013) Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases  Benjamin J Cowling, PhD, Lianmei Jin, MD, Eric HY Lau, PhD, Qiaohong Liao, MD, Peng Wu, PhD, Hui Jiang, MD, Tim K Tsang, MPhil, Jiandong Zheng, PhD, Vicky J Fang, MPhil, Zhaorui Chang, MD, Michael Y Ni, MPH, Qian Zhang, MD, Dennis KM Ip, MPhil, Jianxing Yu, MD, Yu Li, MD, Liping Wang, PhD, Wenxiao Tu, MD, Ling Meng, MD, Joseph T Wu, PhD, Huiming Luo, MD, Qun Li, MD, Yuelong Shu, PhD, Zhongjie Li, MD, Zijian Feng, MD, Weizhong Yang, MD, Yu Wang, PhD, Prof Gabriel M Leung, MD, Dr Hongjie Yu, MD  The Lancet  Volume 382, Issue 9887, Pages 129-137 (July 2013) DOI: 10.1016/S0140-6736(13)61171-X Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 1 Geographical distribution of 130 and 43 laboratory-confirmed cases of human infection with avian influenza A H7N9 and H5N1 viruses in urban and rural areas of mainland China, with dates of illness onset between Nov 25, 2003, and May 3, 2013 Provinces are shaded according to population density, and H7N9 and H5N1 cases. More recent calendar dates of illness onset are represented by symbols. The Lancet 2013 382, 129-137DOI: (10.1016/S0140-6736(13)61171-X) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 2 Occurrence of laboratory-confirmed cases of human infection with avian influenza A H7N9 and H5N1 viruses over calendar time (A) Number of cases of H5N1 in urban and rural residents by calendar year of illness onset. (B) Number of cases of H5N1 in urban and rural residents by calendar month of illness onset. (C) Number of cases of H7N9 in urban and rural residents by date of illness onset. The Lancet 2013 382, 129-137DOI: (10.1016/S0140-6736(13)61171-X) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 3 Age and sex profiles of laboratory-confirmed cases of infection with avian influenza A H5N1 and H7N9 viruses (A) Age and sex profiles for cases of H5N1. (B) Age and sex profiles for cases of H7N9. (C) Age and sex profiles for cases of H5N1 in residents of urban areas. (D) Age and sex profiles for cases of H7N9 in residents of urban areas. (E) Age and sex profiles for cases of H5N1 in residents of rural areas. (F) Age and sex profiles for cases of H7N9 in residents of rural areas. The Lancet 2013 382, 129-137DOI: (10.1016/S0140-6736(13)61171-X) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 4 Comparisons of time-delay distributions for laboratory-confirmed cases of human infection with avian influenza A H7N9 and H5N1 viruses (A) Estimated incubation period distributions—ie, days from infection to illness onset. (B) Days from illness onset to hospital admission. (C) Days from illness onset to laboratory confirmation of influenza A H7N9 or H5N1 virus infection. (D) Days from hospital admission to death. (E) Days from hospital admission to discharge. The Lancet 2013 382, 129-137DOI: (10.1016/S0140-6736(13)61171-X) Copyright © 2013 Elsevier Ltd Terms and Conditions