Plastic Bronchitis: An Old Disease Revisited

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Presentation transcript:

Plastic Bronchitis: An Old Disease Revisited JAMES R. JETT, M.D.  Mayo Clinic Proceedings  Volume 66, Issue 3, Pages 305-311 (March 1991) DOI: 10.1016/S0025-6196(12)61013-1 Copyright © 1991 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Chest roentgenogram obtained at time of admission of 40-year-old man to hospital for evaluation of cough productive of large bronchial casts. Note consolidation of right lower lobe and loss of volume. Mayo Clinic Proceedings 1991 66, 305-311DOI: (10.1016/S0025-6196(12)61013-1) Copyright © 1991 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 2 A, Photograph of expectorated bronchial cast from right lower lobe. B, Representative photomicrograph of bronchial cast. Multiple microscopic sections of the cast were similar in appearance. It was composed of strands of fibrin that were covered with mucus and contained moderate numbers of lymphocytes and foamy histiocytes. Special stains for fungi were negative. (Hematoxylin-eosin; x250.) Although no eosinophils were identified on routine light microscopy, a special stain for eosinophilic granule major basic protein demonstrated occasional foci of eosinophils and extracellular deposition of major basic protein.11 Mayo Clinic Proceedings 1991 66, 305-311DOI: (10.1016/S0025-6196(12)61013-1) Copyright © 1991 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 3 Biopsy specimen from right lower lobe, showing features of an endogenous (obstructive) pneumonia. Bronchiole contained inspissated fibrin and mucus, resembling pattern shown in Figure 2 B. (Hematoxylin-eosin; × 100.) Mayo Clinic Proceedings 1991 66, 305-311DOI: (10.1016/S0025-6196(12)61013-1) Copyright © 1991 Mayo Foundation for Medical Education and Research Terms and Conditions