by Carmen W. van den Berg, and Karolina E. Taylor

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Presentation transcript:

by Carmen W. van den Berg, and Karolina E. Taylor Letter Regarding Article by Li et al, “C-Reactive Protein Upregulates Complement-Inhibitory Factors in Endothelial Cells” by Carmen W. van den Berg, and Karolina E. Taylor Circulation Volume 110(25):e542-e542 December 21, 2004 Copyright © American Heart Association, Inc. All rights reserved.

EA.hy926 cells were incubated for 24 h in medium without additional additives (−); with azide (Az; equivalent to 50 μg/mL CRP=0.0025% azide); Calbiochem CRP (C; 50 μg/mL), dialyzed Calbiochem CRP (C dial; 50 μg/mL); our recombinant azide-free CRP (O; 50 μg/mL); or our recombinant CRP with azide added (O + Az; 0.0025% azide). EA.hy926 cells were incubated for 24 h in medium without additional additives (−); with azide (Az; equivalent to 50 μg/mL CRP=0.0025% azide); Calbiochem CRP (C; 50 μg/mL), dialyzed Calbiochem CRP (C dial; 50 μg/mL); our recombinant azide-free CRP (O; 50 μg/mL); or our recombinant CRP with azide added (O + Az; 0.0025% azide). DAF expression was assessed by flow cytometry. Results are expressed as median fluorescent intensity (MFI)±SD of experiments carried out in triplicate. Statistical analysis was carried out by one-way ANOVA followed by the Tukey multiple comparison test with 95% CI. Carmen W. van den Berg, and Karolina E. Taylor Circulation. 2004;110:e542 Copyright © American Heart Association, Inc. All rights reserved.