C‐Reactive Protein Identifies Low‐Risk Metabolically Healthy Obese Persons: The European Prospective Investigation of Cancer–Norfolk Prospective Population.

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C‐Reactive Protein Identifies Low‐Risk Metabolically Healthy Obese Persons: The European Prospective Investigation of Cancer–Norfolk Prospective Population Study by Diederik F. van Wijk, S. Matthijs Boekholdt, Benoit J. Arsenault, Sara Ahmadi‐Abhari, Nicholas J. Wareham, Erik S. G. Stroes, and Kay‐Tee Khaw J Am Heart Assoc Volume 5(6):e002823 June 3, 2016 © 2016 Diederik F. van Wijk et al.

Distribution of CRP levels according to the number of MS criteria and the presence of abdominal obesity. Distribution of CRP levels according to the number of MS criteria and the presence of abdominal obesity. Plots display the median and 25th and 75th percentiles of the CRP distribution. A Kruskal–Wallis nonparametric test demonstrated P<0.01 between number of MS criteria groups. A Mann–Whitney U test was used to test for significant differences in CRP level within the number of MS criteria groups. ***P<0.01. CRP indicates C‐reactive protein; MS, metabolic syndrome; ns, not significant. Diederik F. van Wijk et al. J Am Heart Assoc 2016;5:e002823 © 2016 Diederik F. van Wijk et al.

CHD event rates according to the number of MS criteria and the presence of abdominal obesity and the presence or absence of an elevated CRP level. CHD event rates according to the number of MS criteria and the presence of abdominal obesity and the presence or absence of an elevated CRP level. A chi‐square test was used to test for differences between event rates between and within the specified groups. To compare differences between the groups with no abdominal obesity and with abdominal obesity, all patients of each MS group were included in the analyses. *P<0.05; ***P<0.01. CHD indicates coronary heart disease; CRP, C‐reactive protein; MS, metabolic syndrome; ns, not significant. Diederik F. van Wijk et al. J Am Heart Assoc 2016;5:e002823 © 2016 Diederik F. van Wijk et al.