A Polymorphism in Interferon L3 Is an Independent Risk Factor for Development of Hepatocellular Carcinoma After Treatment of Hepatitis C Virus Infection

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Presentation transcript:

A Polymorphism in Interferon L3 Is an Independent Risk Factor for Development of Hepatocellular Carcinoma After Treatment of Hepatitis C Virus Infection Kuo-Chin Chang, Po-Lin Tseng, Yi-Ying Wu, Hung-Chao Hung, Chao-Min Huang, Sheng-Nan Lu, Jing-Houng Wang, Chuan-Mo Lee, Chien-Hung Chen, Ming-Chao Tsai, Yi-Hao Yen, Ming-Tsung Lin, Cheng-Kun Wu, Chao-Cheng Huang, Hsiu-Hsi Chen, Tsung-Hui Hu Clinical Gastroenterology and Hepatology Volume 13, Issue 5, Pages 1017-1024 (May 2015) DOI: 10.1016/j.cgh.2014.10.035 Copyright © 2015 AGA Institute Terms and Conditions

Figure 1 Kaplan–Meier analysis of the incidence of hepatocellular carcinoma in chronic hepatitis C virus patients treated with pegylated interferon and ribavirin by patient characteristic. F, fibrotic stage; G1, HCV genotype 1; PLT, platelet count. Clinical Gastroenterology and Hepatology 2015 13, 1017-1024DOI: (10.1016/j.cgh.2014.10.035) Copyright © 2015 AGA Institute Terms and Conditions

Figure 2 Kaplan–Meier analysis of the cumulative incidence of hepatocellular carcinoma in chronic hepatitis C patients after antiviral therapy (A) without and (B) with sustained viral response by IL28B rs12979860 genotype. Clinical Gastroenterology and Hepatology 2015 13, 1017-1024DOI: (10.1016/j.cgh.2014.10.035) Copyright © 2015 AGA Institute Terms and Conditions