The life cycle of the worm involves a carrier, an intermediate host, and a final host.

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Presentation transcript:

Fascioliasis is a foodborne trematode infection caused by Fasciola Hepatica and Fasciola Gigantica.

The life cycle of the worm involves a carrier, an intermediate host, and a final host.

Fascioliasis has three different phases in the final host. Symptomless Incubation Phase (a few days to a few months) Acute Phase (2 to 4 months) Chronic Phase

Although fascioliasis is found worldwide, it is most prevalent in the Andean region (especially Bolivia and Peru), South-East Asia, and Western Europe.

Diagnosis of Fascioliasis can be done by examination of stool samples or by immunological techniques such as a Western Blot or an Enzyme Linked Immunosorbent Assay (ELISA).

Although the precise mechanism of Triclabendazole is unknown, we know that it disrupts micro-tubule based processes by binding to the β-tubulin molecule.

A study done in Vietnam showed that the antimalarial drug Artesunate may have a role in treating fascioliasis.

Reference Antigenic Test For Cattle And Sheep. Tel: +32 (0)84.32.23.77 Fax: +32 (0)84.31.52.63 E-mail: Info@biox.com Http://www.biox.com FASCIOLA HEPATICA ELISA KITA Group of 21 Four-months Old Lambs Was Experimentally Infected with Variable Number of Metacer- (n.d.): n. pag. Web. Fairweather. "Triclabendazole: New Skills to Unravel an Old(ish) Enigma."Journal of Helminthology (2005): 227-34. ProQuest. Web. 12 Apr. 2016. Fairweather. "Triclabendazole Progress Report, 2005–2009: An Advancement of Learning?" Journal of Helminthology (2009): 139-50.ProQuest. Web. 12 Apr. 2016. "Fascioliasis." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, n.d. Web. 12 Apr. 2016. <http://www.cdc.gov/dpdx/fascioliasis/dx.html>. "Fascioliasis." WHO. N.p., n.d. Web. 12 Apr. 2016. <http://www.who.int/foodborne_trematode_infections/fascioliasis/en/>. "Fasciolosis." Wikipedia. Wikimedia Foundation, n.d. Web. 12 Apr. 2016. <https://en.wikipedia.org/wiki/Fasciolosis>. "Global Health PrimerGlobal Health Primer." Fascioliasis. N.p., n.d. Web. 12 Apr. 2016. <http://globalhealthprimer.emory.edu/diseases/fascioliasis.html#transmission>. Hien, Tran Tinh, Ng Thanh Truong, et al. "A Randomized Controlled Pilot Study of Artesunate versus Triclabendazole for Human Fascioliasis in Central Vietnam." The American Society of Tropical Medicine and Hygiene 78.3 (2008): 388-92. Web. 12 Apr. 2016. Jennifer Keiser, Dirk Engels, Gottfried Büscher & Jürg Utzinger (2005) Triclabendazole for the treatment of fascioliasis and paragonimiasis, Expert Opinion on Investigational Drugs, 14:12, 1513-1526, DOI: 10.1517/13543784.14.12.1513 "Parasites - Fascioliasis." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 10 Jan. 2013. Web. 12 Apr. 2016. <http://www.cdc.gov/parasites/fasciola/>.