Mitosis Gone Wild! Tan = Sexy, and Risking Death Cancer Mitosis Gone Wild! Tan = Sexy, and Risking Death

Tan = Sexy?

Tan = Sexy?

Naomi

Tumor Means “swelling” Come to refer to abnormal growth of tissue. Two types of tumors: Benign Malignant

Benign Means “not life threatening” Do not invade other tissues. Do not break apart and spread to other parts of the body (metastasize) Can grow really big and become a serious health problem, possibly life threatening.

Premalignant Benign tumors are at greater risk for turning into “cancer” than other tissue. If they start to “degenerate” then they are called premalignant.

Malignant Cells dedifferentiate – lose specializations like cilia and axons. Metastasize Break away from tumor move through blood stream to other parts of the body Divide and grow into another cancerous tumor.

Cancer Testicle Cells in you Lungs! Breast Tissue in your Brain!

Contact Inhibition Cell to cell contact usually stops cell division, not with cancerous cells.

Oncogenes Genes control cell division – produce checkpoint proteins. Mutations can cause cells to go through mitosis too often = tumor.

Growth Factor Tumor cells either are missing growth factor inhibition or make their own growth factor proteins.

Carcinogens Physical UV Heat Chemical Bind with DNA Biological Viruses