Neurons & Neuroglia Lecture 6.

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Neurons & Neuroglia Lecture 6

Basic Cell Biology Eukaryotic cells Cell membrane Nucleus chromosomes Cytoplasmic organelles Mitochondria Endoplasmic reticulum ribosomes microtubules & microfilaments ~

Neurons Basic functional unit of N.S. Specialized cell All cells have same basic properties Regulation of behavior Information processing Transmits Integrates Stores ~

Dendrites & Soma Receives & Integrates information electrical signal within ~

Axon carries information away from soma Electrical signal within Stimuli Axon carries information away from soma Electrical signal within Axon terminal releases chemical message ~

By function (connections) Sensory Motor Interneuron

By morphology (# of neurites) Multipolar Bipolar Unipolar

Neurons vs. Nerves Neurons - cells microscopic Nerves - bundles of axons seen with naked eye ~

Neuroglia Neural support cells local influence at synapse no role long distance signaling Functions exchange molecules with neurons physical support maintains microenvironment Blood-brain barrier immune system ~

Astrocytes Provide physical support Regulating chemical content of extracellular fluid localizes neurotransmitters K+ concentration Blood-brain Barrier (BBB) ~

BBB: Function Maintains stable brain environment large fluctuations in periphery Barrier to poisons Retains neurotransmitters & other chemicals Regulates nutrient supplies glucose levels active transport ~

Blood-Brain Barrier Brain Capillary astrocytes Typical Capillary Intercellular cleft tight junction Fenestra No fenestra

Neuroglia: Myelin Wrap around axon Saltatory Conduction faster transmission CNS: oligodendrocytes PNS: Schwann cells ~

Microglia Immune-like function macrophage foreign cells cellular debris ~