Finish Readings in Ch 7 Sensory Physiology

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Presentation transcript:

Finish Readings in Ch 7 Sensory Physiology Start Reading Ch 9 Muscle Physiology What’s going on? And what you gonna do about it? Sensory Physiology and Muscle Physiology

Different types of muscles for different tasks! Characteristics: Location, cell shape, nuclei per cell, innervation, connections to adjacent myofibers, arrangement of actin and myosin, regulation of cross bridges, sources of Ca++, response to injury, twitch duration, etc. S 1 09.01.jpg Different types of muscles for different tasks!

S 2

NMJ = neuromuscular junction Myoneural junction Motor end plate S 3 Fig. 09.14 Synonyms: NMJ = neuromuscular junction Myoneural junction Motor end plate S 3 09.14.jpg

Fig. 09.15 S 4 1 AP in motor axon releases sufficient ACh for 1 AP in skeletal muscle. 09.15.jpg Nicotinic EPP Myasthenia gravis and loss of nAChRs

S 5 Capillaries Oxygen, Nutrients, hormones, waste 09.01a.jpg Fig. 09.01a Capillaries Oxygen, Nutrients, hormones, waste 09.01a.jpg

Terms: Myofiber, myofibril, myofilament Fig. 09.11b Terms: Myofiber, myofibril, myofilament 09.11b.jpg Thick myofilament = myosin Thin myofilament = actin

Fig. 09.11a S 7 09.11a.jpg

Fig. 09.12 S 8 High fAP leads to accumulation of Ca++ in sarcoplasm because Ca++ ATPase doesn’t return all Ca++ to SR quickly enough. The concentration of free calcium is directly related to force of contraction in skeletal muscle Thus we need to understand the cellular mechanism of contraction… cell biology flashbacks… 09.12.jpg

Fig. 09.12 S 4 High fAP leads to accumulation of Ca++ in sarcoplasm because Ca++ ATPase doesn’t return all Ca++ to SR quickly enough. The concentration of free calcium is directly related to force of contraction in skeletal muscle Thus we need to understand the cellular mechanism of contraction… cell biology flashbacks… 09.12.jpg