Nabor B. de Moura Júnior, MD, João C. das-Neves-Pereira, MD, Flávio R

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Presentation transcript:

Expression of Acetylcholine and Its Receptor in Human Sympathetic Ganglia in Primary Hyperhidrosis Nabor B. de Moura Júnior, MD, João C. das-Neves-Pereira, MD, Flávio R.G. de Oliveira, MD, Fabio B. Jatene, MD, PhD, Edwin R. Parra, MD, Vera L. Capelozzi, MD, PhD, Nelson Wolosker, MD, PhD, José R.M. de Campos, MD, PhD The Annals of Thoracic Surgery Volume 95, Issue 2, Pages 465-470 (February 2013) DOI: 10.1016/j.athoracsur.2012.10.068 Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Expression of antibody against acetylcholine in hyperhidrotic sympathetic ganglia (brownish) at ×400 magnification. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Expression of antibody against acetylcholine in control sympathetic ganglia (brownish) at ×400 magnification. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Quantification of strong expression of antibody against acetylcholine by group. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Quantification of weak expression of antibody against acetylcholine by group. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Expression of antibody against alpha-7 neuronal nicotinic acetylcholine receptor subunit in hyperhidrotic sympathetic ganglia (brownish) at ×400 magnification. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Expression of antibody against alpha-7 neuronal nicotinic acetylcholine receptor subunit in control sympathetic ganglia (brownish) at ×400 magnification. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 7 Quantification of strong expression of antibody against alpha-7 neuronal nicotinic acetylcholine receptor subunit by group. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 8 Quantification of weak expression of antibody against alpha-7 neuronal nicotinic acetylcholine receptor subunit by group. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 9 Distribution of ganglia diameter by group. The Annals of Thoracic Surgery 2013 95, 465-470DOI: (10.1016/j.athoracsur.2012.10.068) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions