Obstetric and paediatric HIV surveillance data from the UK and Ireland

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Presentation transcript:

Obstetric and paediatric HIV surveillance data from the UK and Ireland

HIV prevalence among pregnant women England and Scotland only, 1997-2012 (PHE, HPS and ICH data)

21,226 pregnancies, diagnosed women since 1990, and reported 21,226 pregnancies, diagnosed women since 1990, and reported* by April 2016

Antenatal screening for HIV and impact

Timing of maternal HIV diagnosis UK & Ireland 1998-2015

Timing of maternal HIV diagnosis UK 1998-2015

Timing of diagnosis & ART at conception UK & Ireland 1998-2015

Sequential pregnancies by conception year, 1998-2014 Pregnancies reported by end April 2016, UK and Ireland

Changing mode of delivery among all diagnosed women Deliveries 2000-2015 reported by end April 2016*, UK births only

Uptake of antiretroviral therapy and MTCT rate by year of birth for 3703 infants born to diagnosed women 1990-2004

MTCT rates in diagnosed women, UK & Ireland 2000-2011

MTCT rates in diagnosed women, UK & Ireland 2000-2011

Infection status of children

Infection status of children born to women diagnosed with HIV before delivery: UK & Ireland Births reported to NSHPC by April 2016

Infection status of children born since 2000 to women diagnosed with HIV before delivery: UK Births reported to NSHPC by April 2016

Infection status of children born since 2000 to women diagnosed with HIV before delivery: Ireland Births reported to NSHPC by April 2016

ART & premature delivery Diagnosed HIV positive women in UK & Ireland, 1990-2005

ART & congenital abnormalities: 1990-2007 data

NSHPC data on congenital abnormalities provided to Antiretroviral Pregnancy Registry (APR)

HIV infection and exposure in children in the UK and Ireland

NSHPC paediatric follow-up protocol

Collaborative HIV Paediatric Study Started in 2000, a collaboration between NSHPC, MRC Clinical Trials Unit and centres looking after infected children

Follow up of uninfected children exposed to ART: CHART study 2002-05

First audit of perinatal HIV transmissions 2002-05

Perinatal HIV audit – UK births since 2006

The role of NSHPC: public health surveillance & epidemiological and clinical research / audit

Ethics MREC/04/2/009