Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression in an Lck-dependent manner. Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression.

Slides:

Advertisements

Similar presentations

NK cells inhibited the expansion and function of ILC2s in vitro via IFN-γ. NK cells inhibited the expansion and function of ILC2s in vitro via IFN-γ. ILC2s.

Advertisements

Activation of NK cells during the early stage of allergic and fibrotic lung inflammation. Activation of NK cells during the early stage of allergic and.

E2F7/8 and HIF1 are required for hypoxic VEGFA expression.

Novel vitamin D3 analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D3, that modulates cell growth, differentiation, apoptosis, cell cycle, and induction of.

Rab11-FIP3 silencing impairs T cell activation events.

Anti-CD40 and CpG induce activation of T cells in draining lymph nodes

Anti–4-1BB/PD-1 combination enriched CD8+ T cells in TILs

(A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza) for 4 d. (A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza)

Proline supplementation during P5CS protein knockdown suppressed GCN2 activation. Proline supplementation during P5CS protein knockdown suppressed GCN2.

Expression and regulation of MD-2s.

MD-2s fails to mediate LPS-dependent NF-κB activation and IL-8 secretion. MD-2s fails to mediate LPS-dependent NF-κB activation and IL-8 secretion. A,

B7-H4 expression correlates with MHC-I expression and improved prognosis in patients with breast cancer. B7-H4 expression correlates with MHC-I expression.

FIP200 maintains microRNA1198-5p expression via Ago2 in naïve T cells.

Nuclear Arp3 mediates formation of TCR-induced nuclear actin filaments

LATS2 promotes death of lumB cells.

Consequences of reducing SF3B2 expression.

FIP200 controls Bak expression via maintaining microRNA1198-5p expression. FIP200 controls Bak expression via maintaining microRNA1198-5p expression. (A)

Interfering with HMGA2 expression blocks transformation in metastatic lung cancer cells. Interfering with HMGA2 expression blocks transformation in metastatic.

The PbGAPDH G6 fragment interacts with recombinant CD68.

Apoptosis and necroptosis of L929 cells results in the release of mitochondria. Apoptosis and necroptosis of L929 cells results in the release of mitochondria.

Collagen-dependent phosphorylation of eIF4E in PDAC cells.

Rapamycin inhibits TCR/CD3 engagement-dependent HIF-1α protein expression. Rapamycin inhibits TCR/CD3 engagement-dependent HIF-1α protein expression. Human.

Effect of expression of constitutively active CAMKK2 on AMPK activation and the cell cycle in G361 cells. Effect of expression of constitutively active.

Volume 18, Issue 3, Pages (March 2010)

Enhanced expression of TLR7 protein in PBMCs from women.

TGFBRAP1 plays a critical role in CHIT1 augmentation of TGF-β1 signaling and TGFβR expression. TGFBRAP1 plays a critical role in CHIT1 augmentation of.

IL-6 neutralization results in induction of CD161+ FOXP3+ CD127– Tregs in EC–CD4+ T cell cocultures. IL-6 neutralization results in induction of CD161+

TCR signaling is required for exhausted-like TRM cell formation and maintenance. TCR signaling is required for exhausted-like TRM cell formation and maintenance.

Western blot analysis of histone H1.X.

Knocking down Wnt3 increases the cells' response to trastuzumab and reduces cells' invasiveness. Knocking down Wnt3 increases the cells' response to trastuzumab.

FIP200 maintains microRNA1198-5p expression via Ago2 in naïve T cells.

Allopurinol up-regulates DR5 expression in PC-3 and DU145 cells.

Downregulation of caveolin-1 by si-RNA in NIH3T3 cells increased survivin expression. Downregulation of caveolin-1 by si-RNA in NIH3T3 cells increased.

Integrin β3 is dispensable for RhoA activity and contractility.

Ectopic expression of caveolin-1 in ZR75 human breast cancer cells downregulated survivin and decreased cell proliferation. Ectopic expression of caveolin-1.

CD151 effects on mammary cell morphology and adhesion.

Dox titration and kinetic analyses of CD19CAR expression upon Dox administration and discontinuation. Dox titration and kinetic analyses of CD19CAR expression.

Overexpression of IL-27 upregulates expression of multiple IR by T cells in vivo. Overexpression of IL-27 upregulates expression of multiple IR by T cells.

Western blotting for GluR1.

Targeting eIF4E increases ZEB1 protein and mRNA levels and decreases ZEB1-targeting miR-200c and miR-141 microRNAs. Targeting eIF4E increases ZEB1 protein.

TFAP2A interacts with HIF-1α and regulates VEGF expression and cell proliferation. TFAP2A interacts with HIF-1α and regulates VEGF expression and cell.

Cell viability assay and expression of COX protein.

Induction of CDCP1 is regulated by Ras in NSCLC cells.

Volume 23, Issue 2, Pages (August 2005)

Mcl-1 knockdown promotes cleavage of caspase-3 in nonadherent melanoma cells. Mcl-1 knockdown promotes cleavage of caspase-3 in nonadherent melanoma cells.

Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. A.

Lamellarin D induces cell death through a Fas-independent pathway.

SiRNA silencing of CDH3, CLDN1, KRT23, and MMP7 (A–D) in adenoma and CRC cell lines significantly reduces cell proliferation. siRNA silencing of CDH3,

Ki-67 expression is dynamically controlled by a cell-cycle–regulatory network. Ki-67 expression is dynamically controlled by a cell-cycle–regulatory network.

CXCR4 expression levels of MDA-MB-231 cells at 48 hours posttransfection of CXCR4 siRNAs. CXCR4 expression levels of MDA-MB-231 cells at 48 hours posttransfection.

Effects of visfatin on the cell proliferation and phosphorylation of ERK, Akt, and GSK-3β proteins in HCC cells. Effects of visfatin on the cell proliferation.

Expression of CRC stem cell markers and L1 in CRC cells.

Ectopic expression of CA RSK1 mutant protects melanoma cells from PD98059-mediated apoptosis. Ectopic expression of CA RSK1 mutant protects melanoma cells.

TFAP2A knockdown inhibits cell growth by targeting HIF-1α signaling.

Biological effects of BRAF silencing: growth curves of A375 (A) and ARO (B) cell lines in the absence or presence of doxycycline. Biological effects of.

IGF-IR in human head and neck cancer.

ALT-803 stimulates proliferation and activation of human NK cells and T cells in vitro. ALT-803 stimulates proliferation and activation of human NK cells.

Pirh2 represses p73-dependent transactivation.

Expression of B7-H1, B7-DC, and PD-1 on B cells.

The effects of HDAC2 knockdown on cell-cycle proteins.

Met is expressed in Her2-overexpressing cell lines and Her2 (+) breast tumors. Met is expressed in Her2-overexpressing cell lines and Her2 (+) breast tumors.

Local proliferation of infiltrating circulating memory T cells.

Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Expression.

AS1411 alters subcellular distribution of PRMT5 in a time-dependent, dose-dependent, and nucleolin-dependent manner. AS1411 alters subcellular distribution.

Combination of R848 and anti-CD200R affects activation of tumor-infiltrating myeloid cells. Combination of R848 and anti-CD200R affects activation of tumor-infiltrating.

PARP1 suppresses the transcription of PD-L1 in cancer cells.

MPD-L1–transfected 300 cells do not bind to mB7-1–transfected 300 cells. mPD-L1–transfected 300 cells do not bind to mB7-1–transfected 300 cells. Cell-to-cell.

Coculture with U937 cells enhances DNMT1 expression in gastric cancer cells. Coculture with U937 cells enhances DNMT1 expression in gastric cancer cells.

Silencing E4BP4 abrogates the promoting effect of SMAD3 knockdown on IFNγ production in NK-92 cells. Silencing E4BP4 abrogates the promoting effect of.

Sp1 complementation assay.

Presentation transcript:

Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression in an Lck-dependent manner. Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression in an Lck-dependent manner. (A) Jurkat T cells were transfected with two-by-two combinations of control, Lck, and FIP3.1 siRNA oligonucleotides. CD3 cell surface expression was then assessed by flow cytometry. Measurements are expressed as percentage of staining of cells transfected with control siRNA. Mean of triplicates ± SD, Mann–Whitney U test. Representative of three experiments. (B) FIP3 protein expression was analyzed by Western blot with respect to a nonspecific band of 37 kDa, used here as a loading control. ***p < 0.001, n.s.p ≥ 0.05. Jérôme Bouchet et al. J Immunol 2017;198:2967-2978 Copyright © 2017 by The American Association of Immunologists, Inc.