Silent Brain Infarcts by Yi-Cheng Zhu, Carole Dufouil, Christophe Tzourio, and Hugues Chabriat Stroke Volume 42(4):1140-1145 March 28, 2011 Copyright ©

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Silent Brain Infarcts by Yi-Cheng Zhu, Carole Dufouil, Christophe Tzourio, and Hugues Chabriat Stroke Volume 42(4):1140-1145 March 28, 2011 Copyright © American Heart Association, Inc. All rights reserved.

Main signal characteristics used for defining SBI on different MRI sequences. Main signal characteristics used for defining SBI on different MRI sequences. A–D, A silent brain infarct (SBI) corresponds to CSF signal on all MRI sequences (black arrows). A, Axial T2-weighted; (B) axial T1-weighted; (C) axial fluid-attenuated inversion-recovery (FLAIR); (D) axial proton density. E–H, A hyperintense lesion on T2-weighted images that is moderately hypointense on T1 in the left thalamus (white arrows) is not defined as SBI in studies defining only cavities containing CSF as infarcts, whereas it is diagnosed as an infarct in studies that simply defined hyperintense T2 and hypointense T1 foci as infarcts. E, Axial T2-weighted; (F) axial T1-weighted; (G) axial FLAIR; (H) axial proton density. CSF indicates cerebrospinal fluid. Yi-Cheng Zhu et al. Stroke. 2011;42:1140-1145 Copyright © American Heart Association, Inc. All rights reserved.