Comparative Effectiveness of Platelet-Rich Plasma Injections for Treating Knee Joint Cartilage Degenerative Pathology: A Systematic Review and Meta-Analysis Ke-Vin Chang, MD, Chen-Yu Hung, MD, Fanny Aliwarga, MD, Tyng-Guey Wang, MD, Der-Sheng Han, MD, PhD, Wen-Shiang Chen, MD, PhD Archives of Physical Medicine and Rehabilitation Volume 95, Issue 3, Pages 562-575 (March 2014) DOI: 10.1016/j.apmr.2013.11.006 Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions
Fig 1 Flow diagram of the evaluation process for the inclusion or exclusion of studies. Archives of Physical Medicine and Rehabilitation 2014 95, 562-575DOI: (10.1016/j.apmr.2013.11.006) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions
Fig 2 Forest plot of the ES of functional changes from baseline at (A) 2 months, (B) 6 months, and (C) 12 months after PRP injections. Abbreviation: ES, effect sizes. Archives of Physical Medicine and Rehabilitation 2014 95, 562-575DOI: (10.1016/j.apmr.2013.11.006) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions
Fig 3 Forest plot of the ES of functional changes from baseline after HA injections. Abbreviation: ES, effect sizes. Archives of Physical Medicine and Rehabilitation 2014 95, 562-575DOI: (10.1016/j.apmr.2013.11.006) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions
Fig 4 Temporal relationships of effect sizes of functional changes after PRP, HA, and placebo injections. We also analyzed the treatment arm only comprising RCT of PRP interventions. Abbreviation: RCT, randomized controlled trials. Archives of Physical Medicine and Rehabilitation 2014 95, 562-575DOI: (10.1016/j.apmr.2013.11.006) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions
Fig 5 Funnel plots of the effective size of functional changes from baseline at (A) 2 months, (B) 6 months, and (C) 12 months after PRP injections. Archives of Physical Medicine and Rehabilitation 2014 95, 562-575DOI: (10.1016/j.apmr.2013.11.006) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions