Recovery of hypoplastic left heart syndrome (HLHS) mutant by ultrasound phenotyping. Recovery of hypoplastic left heart syndrome (HLHS) mutant by ultrasound.

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Presentation transcript:

Recovery of hypoplastic left heart syndrome (HLHS) mutant by ultrasound phenotyping. Recovery of hypoplastic left heart syndrome (HLHS) mutant by ultrasound phenotyping. Vevo2100 in sagittal view (A) showed an E16.5 fetus with reversed aortic blood flow. This is seen in the diastole (B) and confirmed by spectral Doppler (C). Vevo2100 imaging in the short-axis view (D) showed hypoplastic left ventricle. Necropsy of the stillborn pup (E) revealed hypoplastic aorta (Ao) and small left ventricle, confirmed by episcopic fluorescence image capture histology (F and G) to be HLHS with small mitral valve orifice, small left ventricle, and hypoplastic aorta. DA indicates ductus artery; and DAo, descending aorta. Scale bar, 1 mm. A indicates anterior; Cd, caudal; Cr, cranial; L, left; P, posterior; and R, right. Xiaoqin Liu et al. Circ Cardiovasc Imaging. 2014;7:31-42 Copyright © American Heart Association, Inc. All rights reserved.