David McD. Taylor, MD, MPH, Celene Y. L. Yap, MSc, Jonathan C

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Presentation transcript:

Midazolam-Droperidol, Droperidol, or Olanzapine for Acute Agitation: A Randomized Clinical Trial David McD. Taylor, MD, MPH, Celene Y.L. Yap, MSc, Jonathan C. Knott, MBBS, PhD, Simone E. Taylor, PharmD, Georgina A. Phillips, MBBS, Jonathan Karro, MBBS, Esther W. Chan, BPharm, PhD, David C.M. Kong, BPharm, PhD, David J. Castle, MD Annals of Emergency Medicine Volume 69, Issue 3, Pages 318-326.e1 (March 2017) DOI: 10.1016/j.annemergmed.2016.07.033 Copyright © 2016 American College of Emergency Physicians Terms and Conditions

Figure 1 Patient flow through the study (modified CONSORT diagram). *Patients aged 15 and 71 years. †Patients aged 68 and 69 years. ‡Patient sedation difficult and unblinding undertaken to inform clinical decisionmaking. No unblinding was undertaken in response to adverse events. Annals of Emergency Medicine 2017 69, 318-326.e1DOI: (10.1016/j.annemergmed.2016.07.033) Copyright © 2016 American College of Emergency Physicians Terms and Conditions

Figure 2 Kaplan-Meier curve comparing the proportion of patients sedated as a function of time. The vertical line is at 10 minutes, with the proportion sedated at the time of the primary outcome of the study. Annals of Emergency Medicine 2017 69, 318-326.e1DOI: (10.1016/j.annemergmed.2016.07.033) Copyright © 2016 American College of Emergency Physicians Terms and Conditions