Chapter 15 – The Chromosomal Basis of Inheritance

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Presentation transcript:

Chapter 15 – The Chromosomal Basis of Inheritance

Sex Determination

Sex-linked genes

Sex linked inheritance Must show sex chromosomes Hemizygous

X inactivation Barr body

Linked genes

Nondisjunction Aneuploidy Monosomy Trisomy

Down syndrome

Trisomies in sex chromosomes Klinefelter syndrome 47, XXY Jacob syndrome 47, XYY TriploX 47, XXX

Monosomy in sex chromosome Turner syndrome 45, XO

Chromosome structural abnormalities Deletion Duplication

Chromosome structural abnormalities cont Inversion Translocation