HMPREF0351_10908 10909 10910 10911 10912 10913 10914 10915 10916 10917 10918 10919 10920 10921 10922 10923 HMPREF9522_02513 TX16; 1,230,933; 1,231,502;

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HMPREF0351_10908 10909 10910 10911 10912 10913 10914 10915 10916 10917 10918 10919 10920 10921 10922 10923 HMPREF9522_02513 TX16; 1,230,933; 1,231,502; E980; 1,231,410; U0137 02512 02511 02510 02509 02508 02507 02506 02505 02504 TX82; TX0133A; 1,231,408; C68; D344SRF; E1162 HMPREF0352_0448 0449 0450 0451 0452 0453 0454 0455 0456 0457 TX1330; Com12 1,141,733 1,231,501 E1071 EFWG_01379 01378 01377 01376 01375 01374 01373 01372 01371 01370 Com15; E1679 E1636 E1039 B 1 B B A B 2 3 B 4 A B Supplemental Figure- ORF composition of the downstream extension of the epa gene cluster in the 22 E. faecium genomes (HMPREF0351_10908 - HMPREF0351_10923 in TX16). The predicted polysaccharide-encoding gene clusters can be divided into four main groups (Locus 1-4) based on sequence similarities; shades of the same color indicate similar sequences. Vertical lines connect orthologs of different groups. Letters A and B indicate orthologs of HMPREF0351_10908 and HMPREF02513_02513, respectively. Gene locus tags of each group are based on the respective strain in bold (Locus 1, Com15; Locus 2, TX1330; Locus 3, TX82; Locus 4, TX16). CA -clade strains are indicated by red font.