A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis.

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Presentation transcript:

A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids Tetsuo Nakayama, MDa, Chikara Aizawa, PhDa, Harumi Kuno-Sakai, MDb Journal of Allergy and Clinical Immunology Volume 103, Issue 2, Pages 321-325 (February 1999) DOI: 10.1016/S0091-6749(99)70508-7 Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 1 Immunization schedules in Japan and the US. Journal of Allergy and Clinical Immunology 1999 103, 321-325DOI: (10.1016/S0091-6749(99)70508-7) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 2 Onset of various allergic symptoms after vaccination. Journal of Allergy and Clinical Immunology 1999 103, 321-325DOI: (10.1016/S0091-6749(99)70508-7) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 3 Detection of IgE antibodies to gelatin. Gelatin-specific IgE antibodies less than 0.34 Ua/mL are considered as negative. The numbers of IgE antibodies considered negative are shown under open circles. Filled circles show individual gelatin-specific IgE antibody levels by the category of adverse reaction or control. The positivity of gelatin-specific IgE antibodies is shown under the categories of adverse reactions. Journal of Allergy and Clinical Immunology 1999 103, 321-325DOI: (10.1016/S0091-6749(99)70508-7) Copyright © 1999 Mosby, Inc. Terms and Conditions