Do now activity Explain which DNA bases pair together? How many hydrogen bonds are formed between each pair? List all 3 steps of DNA Replication in order. Explain what it means when DNA is “semi-conservative”. Why is the DNA structure semi-conservative? Explain each step of the Cell Cycle ( G 1 , S, G 2 , M). Why do cells need to go through mitosis? What is a consequence if they do not go through mitosis?

Section 3-3: Transcription Essential Question Compare and contrast the difference and similarities between DNA and RNA. Learning Targets Explain how the structure of DNA determines the structure of proteins. Develop a model demonstrating the creation of a protein from DNA that includes the macromolecules and organelles involved Section 3-3: Transcription

announcements Biology Tutoring schedule W&F @ 7:00AM Section 3 Quiz 1 Scheduled for Thursday: 10/19/17 Section 3 Lab Scheduled for Monday & Tuesday: 10/23 & 10/24 Class website will be updated today

Available Extra Credit announcements Available Extra Credit 1 Ream of Colored Printer Paper = 1 Class Pass (Limit 1 per student per chapter)

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overview Function of RNA: to move genetic information from the ___ to the ___ for protein synthesis. Nucleus/cytoplasm nucleus cytoplasm

RNA structure is made of _____ . overview nucleotides RNA structure is made of _____ . nucleotides

overview 3 Types of RNA 1. mRNA 2. rRNA 3. tRNA cyclins

“messenger” mRNA – transcribes DNA’s message overview cyclins “messenger” mRNA – transcribes DNA’s message

“ribosomal” rRNA – translates the mRNA overview cyclins “ribosomal” rRNA – translates the mRNA

“transfer” tRNA – carries amino acids overview cyclins “transfer” tRNA – carries amino acids

The picture is most similar to what type of RNA? Question #1 The picture is most similar to what type of RNA? cyclins

The picture is most similar to what type of RNA? Question #2 The picture is most similar to what type of RNA? cyclins

The picture is most similar to what type of RNA? Question #3 The picture is most similar to what type of RNA? cyclins

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The sugar is ______ in RNA. How is it different? ribose The sugar is ______ in RNA. ribose

How is it different? single RNA is ______ stranded. single

RNA uses _____ instead of Thymine. How is it different? Uracil RNA uses _____ instead of Thymine. Uracil

Tell me about the picture. Defend your answer. Question #4 Tell me about the picture. Defend your answer. DNA because: double stranded, base T

Tell me about the picture. Defend your answer. Question #5 Tell me about the picture. Defend your answer. RNA because: single stranded, base U

How is it different? DNA G C T A RNA C G A U

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Protein: made up of _____ ______ Protein synthesis Amino Acids Synthesis: “to make” Protein: made up of _____ ______ amino acids

mRNA is transcribed from DNA Protein synthesis Step #1 mRNA is transcribed from DNA

Protein synthesis Step #2 mRNA leaves nucleus

mRNA travels to a ribosome Protein synthesis Step #3 mRNA travels to a ribosome

The rRNA translates the mRNA Protein synthesis Step #4 The rRNA translates the mRNA

tRNA brings the correct ___ ___. Protein synthesis Amino Acid Step #5 tRNA brings the correct ___ ___. amino acid

the amino acids link together to form a protein Protein synthesis Step #6 the amino acids link together to form a protein

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transcription C A T G DNA Strand “information” During Transcription, mRNA copies the information stored in DNA to be used for protein synthesis.

To copy DNA, RNA nucleotides are added. transcription G C RNA nucleotides added U A C G A T DNA Strand “information” To copy DNA, RNA nucleotides are added.

RNA nucleotides will pair RNA bases with the complementary DNA bases. transcription C C G A T DNA Strand “information” RNA nucleotides will pair RNA bases with the complementary DNA bases.

transcription DNA Strand “information” covalent bond formed catalyzed by RNA polymerase C C C G A T DNA Strand “information”

transcription C C U C G A T DNA Strand “information”

transcription C C U G C G A T DNA Strand “information”

transcription C C U G A C G A T DNA Strand “information”

transcription C C U G A A C G A T DNA Strand “information”

transcription C C U G A A G C G A T DNA Strand “information”

transcription C C U G A A G A C G A T DNA Strand “information”

transcription C U A G C G A T DNA Strand “information”

Once Transcription is finished, the New Strand forms mRNA. New Strand is part of messenger RNA C C U G A A G A G C G A T DNA Strand “information” Once Transcription is finished, the New Strand forms mRNA.

transcription C A T G DNA Strand “information” code for an amino acid

transcription DNA Strand “information” C A T G code for another amino acid

“CODON” : Every 3 bases on the mRNA is a code for an amino acid. transcription mRNA C U A G Codon Codon Codon “CODON” : Every 3 bases on the mRNA is a code for an amino acid.

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Protein Synthesis Project Fold your white piece of paper in half (hamburger style). Fold it in half again (hamburger style). Draw in the creases with pencil to form 4 equal boxes on each side. Number each box in the lower right hand corner (#’s 1 – 8).

Protein Synthesis Project Box 1: Title Page : “Protein Synthesis Project” : By: Student Name : Color Box 2: Explain why DNA is important for protein synthesis. Box 3: Step #1 (copy from your notes) Box 4: Step #2 (copy from your notes)

Protein Synthesis Project Box 5: Step #3 (copy from your notes) Box 6: Step #4 (copy from your notes) Box 7: Step #5 (copy from your notes) Box 8: Step #6 (copy from your notes) Once you are done writing down the text, pick a theme and draw a picture that appropriately symbolizes the process of Protein Synthesis (i.e. Spongebob, Avengers, etc.)