The Effect of Intra-Articular Steroids on Cartilage in Knee Osteoarthritis.

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Presentation transcript:

The Effect of Intra-Articular Steroids on Cartilage in Knee Osteoarthritis

This program will include a discussion of investigational agents not approved by the FDA for use in the United States.

Goals of This Program

Background

Background (cont)

Historic Perspectives: Effect of IA Steroids on Knee Cartilage

Historic Perspectives: Effect of IA Steroids on Knee Cartilage (cont)

Effect of IA Steroids on Articular Cartilage

Effect of IA Steroids on Articular Cartilage: Panel’s Comments

Effect of IA Steroids on Articular Cartilage: Panel’s Comments (cont)

OA Is a Disease Process, Not a Condition

Early Anti-inflammatory Treatment in Patients With Acute ACL Tear

Early Anti-inflammatory Treatment: Methods

Early Anti-inflammatory Treatment: Results

Early Anti-inflammatory Treatment: Conclusions

Can IA Triamcinolone Modify OA Progression?

Can IA Triamcinolone Modify OA Progression? Results

Can IA Triamcinolone Modify OA Progression? Conflicting Conclusions

Can IA Triamcinolone Modify OA Progression? Panel’s Comments

Can IA Triamcinolone Modify OA Progression? Panel’s Comments (cont)

Analgesic Effect of ER Triamcinolone

Analgesic Effect of ER Triamcinolone: Results

Analgesic Effect of ER Triamcinolone: Implications

Analgesic Effect of ER Triamcinolone: Implications (cont)

Summary

Abbreviations