Midterm-Review Meeting Molecular Machines- Design and Nano-Scale Handling of Biological Antetypes and Artificial Mimics Work Package 3: Electro-Engines Design, synthesis and handle the first artificial ATPase-like molecular motors Objectives Partners ULP CIAM TU/e MPI-FKF PM TU/e : 4 PM Specific Targeted Research Project (STREP) in FP6-NMP-2002

Midterm-Review Meeting Work Package 3: Electro-Engines A new idea is tested to have chemical energy to move a multivalent molecule Dynamic Covalent Chemistry with dendrimers is tested All five generations can be made Modified surfaces are prepared Gradients in surface modification are achieved in collaboration with prof. Reinhoudt (UTwente). Directional movement of dendrimers is demonstrated Verification of experiments should be performed New idea should be discussed with partners All results are presented on poster T. Chang Specific Targeted Research Project (STREP) in FP6-NMP-2002

Dynamic Covalent Chemistry Oxime Formation Hydrolysis and Exchange Rowan, S. J.; Cantrill, S. J.; Cousins, G. R. L.; Sanders, J. K. M.; Stoddart, J. F. Angew. Chem., Int. Ed. 2002, 41, 899-952. Theresa Chang