Incorporating New Therapies in IBS-C

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Presentation transcript:

Incorporating New Therapies in IBS-C

Patient Case

Is it Irritable Bowel Syndrome With Constipation?

What is IBS?

Pathophysiology of IBS

When Constipation Does Not Respond to First-line Treatment

IBS Diagnostic Testing

Cornerstones of Treatment for the Patient With IBS

Are Behavioral Therapies Useful in IBS?

Antispasmodics, Antidepressants, Laxatives

New and Emerging Treatments

Long-term Efficacy of Lubiprostone: Monthly Responder Rates

Effects of Guanylate Cyclase-C Receptor Activation

Linaclotide for IBS-C: Adequate Relief of IBS Symptoms for ≥ 13/26 Weeks

Prucalopride for Chronic Constipation Post-hoc Analysis of Phase III Data From Patients Who Had Failed Previous Laxative Therapies

Elobixibat: Mechanism of Action

Patient Case: Conclusion

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)

References (cont)