Intestinal Parasitic Protzoa
Entamoeba histolytica/Trophozoite
Entamoeba Trophozoite with food vacuoles
Entamoeba histolytica cyst
Giardia lamblia
Giardia lamblia
Nyctotherus
Balantidium coli morphology Balantidium is the largest protozoan and only ciliate known to parasitize humans 3
Balantidium coli Diagnosis History, symptoms and finding the typical trophozoites and cysts in the stool 5
African Trypanosomiasis Sleeping Sickness Trypanosoma brucei brucei (cattle) Trypanosoma brucei gambiense Trypanosoma brucei rhodesiense American Trypanosomiasis Chagas Disease Trypanosoma cruzi
Dr.T.V.Rao MD
African Sleeping Sickness
Reduviidae transmit the infection Triatomines, which transmit T cruzi, belong to the family Reduviidae in the order Hemiptera. Reduviidae has 22 subfamilies, including the Triatominae Dr.T.V.Rao MD
Trypanosoma cruzi and Chagas’ Disease The etiological agent of Chagas’ disease is the intracellular protozoan parasite Trypanosoma cruzi (T. cruzi), which is transmitted by the insect vector Triatoma infestans (reduviid bug) Reduviid bugs live in mud filled walls of huts in rural areas The bug bites human hosts and transmits the parasite Triatoma infestans (Reduviid bug) Trypanosoma cruzi with human erythrocytes Dr.T.V.Rao MD
PROMASTIGOTES AMASTIGOTES
Questions Consider the nature of both diseases; their vector, distribution and impact on local populations. Which disease, in your opinion, deserves more attention and funding? Why? How would you invest the money?
Tse tse fly/Glossina
Promastigote
A macrophage filled with Leishmania amastigotes:
Phlebotumine sandfly Size: 2 – 3 mm 500 Species, (30 LEISHMANIA)
Vector of Leishmania PhlebotomusSand fly(sandfly ) Larvae of sandfly
Sand fly/ Phelobotomus