SIGNAL TRANSDUCTION Signal Transduction Pathway Protein Modification Phosphorylation Cascade Protein Kinases.

Slides:



Advertisements
Similar presentations
Chapter 11 Cell Communication
Advertisements

Lecture 4 Outline (Ch. 9) I.Cell Signaling Overview II.Signal Transduction III. General Cell Responses IV. Reception in Detail V.Transduction in Detail.
Cell Communication Chapter 11:. Why do cells communicate? Regulation - cells need to control cellular processes. Environmental Stimuli - cells need to.
Cell Communication (Signaling) Part 2
Signaling and the Signal Transduction Cascade. Question?????? External Stimulus Inside cell Nucleus, Gene transcription Other cellular effects.
Signal Pathways in Eukaryotic Cells Overview. Lipid Soluble Hormones.
Chem 509 Signal Transduction Winter 2010 Lecture 1.
Receptors Lesson 8. Ligands & Receptors n Ligand l neurotransmitters l drugs n Receptor proteins l ligand binds to multiple receptors l receptor subtypes.
B. Signal Transduction Pathway (cell signaling)
Chapter 6-10 AP Biology. Define phagocytosis and pinocytosis. What does it mean for a cell to have a concentration gradient?
Three Stages The process in which a signal on the outside of a cell is turned in to a specific cellular response on the inside of a cell is called a signal.
Cell Signaling basics.
CHAPTER 13 Insulin Signaling. Figure 13.1 – General mechanism of signal transduction across a membrane Steps involved: 1. Release of primary messenger.
Signal Transduction and Secondary Messengers Mahmoud Farhat.
CAMP Controls Activity of Protein Kinase A R C R C R R A A A A A A A A C C Regulatory subunits Catalytic subunits cAMP Active kinase C CREB P Nucleus Activation.
Signal Transduction Lecture 14. Ligands & Receptors n Ligand l Neurotransmitters & drugs n Receptor proteins l ligand binds to multiple receptors n Binding.
Unit 2 – The Cell Chapter 11~ Cell Communication.
Cell Signaling Cells communicate in various ways. – The type of communication used by each cell is based on the type of information that needs to be passed.
Cell Signaling. Local Signaling Paracrine Paracrine Synaptic Synaptic.
Presynaptic Axon Terminal Postsynaptic Membrane Terminal Button Dendritic Spine.
Cell Signaling How to Get a Message from the outside of the Cell to the inside of the cell.
11.3 Transduction: Cascades of molecular interactions relay signals from receptors to target molecules in the cell  Signal transduction usually involves.
Chapter 11 Cell Communication. Cell communication signal cells communicate by direct contact or by secreting local regulators ex: growth factors, neurotransmitters.
Chapter  Differentiate between the following:  Paracrine  Endocrine  Autocrine.
Chapter 11 Cell Communication. Local signaling: Paracrine Synaptic Long distance signaling: Hormonal. Chapter 11 Cell Communication.
Cellular Communication Objectives 1. Learn how external signals are turned into cell responses 2.Learn the role of receptor proteins in communication 3.Learn.
Cellular Signaling Section 2-3. Discussion Points: What happened? How did you recognize where to go? How does this model cell communication? What effect.
Signal transduction. General scheme There are two general types of receptors: cell-surface and intracellular receptors.
Chapter 5.6+ Cellular Biology
Cell Communication.
3.D.3 Signal Transduction Signal transduction pathways link signal reception with cellular response.
Cell Communication Chapter 11.
3.D.1 Cell Communication Reflects Shared Ancestry
Cell Communication.
Ch. 14 Part 6 Cell Signaling.
Cellular Signaling Ch. 11.
Cell Communication Part II
Chapter 11 – Cell Communication
Cell Communication Review
Chapter 11 Cell Communication.
Concept 4: Analyzing Cell Communication
Concept 4: Analyzing Cell Communication
Chapter 11~ Cell Communication
Chapter 11 Cell Communication.
Chapter 11~ Cell Communication
Cell Communication.
Cell Communication (Signaling) Part 2
You have identified a novel cytoplasmic protein
Cell Communication (Signaling) Part 2
Eric Niederhoffer SIU-SOM
Cell Communication Chapter 11 Study the diagrams!!
Cell Communication REVIEW.
Chapter 11 Cell Communication
Signal Transduction Dr. Nasim.
Cell Communication.
Cell Communication (Signaling) Part 2
Regulation of Metabolism
Lipid Soluble Hormone.
Cell Communication CHAPTER 11.
Chapter 11~ Cell Communication
Cell Communication (Signaling) Part 3
Cell Communication (Signaling) Part 2
Cell Communication (Signaling) Part 3
Regulation of Metabolism
Signal Transduction Lecture 14. Ligands & Receptors n Ligand l Neurotransmitters & drugs n Receptor proteins l ligand binds to multiple receptors n Binding.
Chapter 11 A. Cell Signals Cell signaling has evolved over time
Transduction mechanisms
Cell Communication.
Review Quiz Please open this review in a slide show mode. Answer a question first, then go to the next slide for the correct answer.
Presentation transcript:

SIGNAL TRANSDUCTION

Signal Transduction Pathway Protein Modification Phosphorylation Cascade Protein Kinases

Receptor transduction G-Protein Secondary Messenger Cell Target cAMP

G protein: Protein Phosphorylation R G GDP ACAC PK

G protein: Protein Phosphorylation R ACAC PK G GTP ATP cAMP

G protein: Protein Phosphorylation R ACAC PK G GTP ATP cAMP P

G protein: Protein Phosphorylation R ACAC PK G GTP ATP cAMP P Pore